“allergic reaction welts _treatment for urticarial vasculitis”

Text: “Skin Conditions: Hives (Urticaria and Angioedema)”,- WebMD Medical Reference provided in collaboration with the Cleveland Clinic,”Understanding Hives- Treatment”, – WebMD Medical Reference, “Allergic Reaction”- WebMD Medical Reference from eMedicineHealth
Apply calamine lotion. Calamine lotion is a mixture of zinc oxide and zinc carbonate. It can be applied to hives to relieve the itching as often as needed. When the itching subsides or you want to reapply, rinse off the calamine lotion with cool water.[13]
Discovering the exact cause of chronic urticaria is often extremely difficult. If the hives occur daily, they are most likely caused by something that you are exposed to daily. In that case, it is easier to see the cause/effect relationship. Sometimes it is several hours after exposure before the itching begins. In that case, some real detective work will be needed to find the culprit. These are the things to consider in order of importance: foods, drugs, infections, inhalants, and psychological factors.
There is a lot that we still do not understand about urticaria causes although we do know that there are certain triggers and certain reactions that could cause the symptoms associated with utricaria to flare up. The absence of any well defined or clear cause of urticaria does to a large extent limit our ability to deal with the problem. The point to note is that urticaria is not always caused through or because of an allergy and there is no definitive urticaria cure. Non–allergic causes are connected to auto- immunity, to hormone interplay to stress factors, and more. These are some of the more common urticaria causes or triggers:
; hives intensely itchy skin wheals; arise as hypersensitivity reaction, or on exposure to trigger substances (e.g. in foods, plants, drugs or other agents), or due to uraemia; characteristic of anaphylaxis
The hallmark red raised welts of hives sometimes have a pale center, can appear in clusters, and can change shape and location in a matter of hours. They can be from a few millimeters wide to as big as a dinner plate, and can itch, sting, or cause a burning sensation.
Most of the time, a doctor can diagnose hives just by looking at the skin. To find the cause, you may be asked questions about your child’s medical history, recent exposure to allergic triggers, and daily stressors.
Hives can be caused by an allergic reaction to foods, drugs, insect bites, infections or substances which can cause other allergic reactions. However not all cases are caused by allergy; frequently they are caused by viruses. It can sometimes be extremely difficult to find the cause. Triggers include medications, food, viruses, latex, heat, cold and direct exposure to sun. If the cause is known, the trigger should be avoided.
When you’re all stressed out, your body releases hormones and other chemicals, including histamine, the powerful chemical that leads to allergy symptoms. While stress doesn’t actually cause allergies, it can make an allergic reaction worse by increasing the histamine in your bloodstream.
In a small percentage of patients with chronic urticaria, perhaps about 2% [71], there is an underlying small vessel vasculitis. It is important to diagnose these patients because they may have an associated systemic illness which can lead to severe complications and because the treatment of urticarial vasculitis differs from that of ordinary chronic urticaria. Clinically, the lesions of urticarial vasculitis are longer-lasting (3–7 days) than those of ordinary chronic urticaria. They are often painful or ‘burning’ and they may leave residual bruising or hyperpigmentation of the skin. Approximately 40% of patients with urticarial vasculitis will have associated angioedema. Urticarial vasculitis may occur at any age, but the median age of incidence is 43 years. Women are affected twice as often as men. Two categories of urticarial vasculitis are recognized – hypocomplementaemic and normocomplementaemic [72]. Patients with hypocomplementaemic urticarial vasculitis syndrome (HUVS) are more likely to have an associated connective tissue disease and systemic symptoms than patients with normal complement levels [73] and may have IgG antibodies to the collagen-like domain of C1q [74]. There may be associated fever, arthralgia (50%), gastrointestinal involvement with abdominal pain, nausea, vomiting and diarrhoea (20%); pulmonary disease with dyspnoea or pulmonary effusions (20%); and glomerulonephritis with haematuria and proteinuria (5–10%). Progressive renal disease is rare, unless the urticarial vasculitis is associated with SLE. Other rare manifestations include eye involvement, lymphadenopathy, splenomegaly and pericardial effusions.
Yet another consideration is if you have an allergy to latex because a number of foods are known to produce a cross-reaction. Foods on this list include avocado, bananas, chestnuts, kiwi, and passion fruit.
Contrary to this opinion, William E. Berger, MD, MBA, professor of medicine at the University of California, tells WebMD that allergies create stress because you cannot focus on tasks and your coping skills decline.
Urticaria affects almost 20 percent of the population but the majority of the time, the cause is unknown (idiopathic). Even so, it is a good idea to try to find the trigger so you can possibly avoid it in the future.
Acute urticaria may develop in relation to a particular stressful event and it is recognized that financial, personal or professional stress may all worsen chronic urticaria. The condition itself may be very debilitating and it reduces quality of life [36].
Urticaria typically looks like a raised rash that may be a normal skin colour or pinkish or red in colour. The rash may occur anywhere on the body and often starts off as small round spots that quickly enlarge and spread.
Urticarial lesions itch, have a central white wheal that is elevated, and are surrounded by an erythematous halo. The lesions are typically rounded and circumscribed. Characteristically, hives should blanch with pressure; they generally resolve within 24 hours, leaving no residual change to the skin. The redness, which is augmented by local neural reflexes, is due to dilated blood vessels in superficial layers of the skin; the wheal is due to leakage of these vessels as fluid extravasates and compresses the vessels beneath it so that the central area appears clear.
Pressure-induced urticaria typically occurs 4-6 hours after pressure has been applied. Patients may complain of swelling secondary to pressure with normal-appearing skin (i.e., no erythema or superficial infiltrating hive), so that the term angioedema is more appropriate. Others are predominantly urticarial and may or may not be associated with significant swelling. Symptoms occur about tight clothing; the hands may swell with activity such as hammering; foot swelling is common after walking in patients with normal heart function; and buttock swelling may be prominent after sitting for a few hours.
Urticaria, commonly referred to as hives, is the most frequent dermatologic disorder seen in the emergency department (ED). It appears as raised, well-circumscribed areas of erythema and edema involving the dermis and epidermis that are very pruritic. Urticaria may be acute (lasting <6 wk) or chronic (lasting >6 wk). A large variety of urticaria variants exist, including acute immunoglobulin E (IgE)–mediated urticaria, chemical-induced urticaria (non-IgE-mediated), autoimmune urticaria, cholinergic urticaria, cold urticaria, mastocytosis, periodic fever syndromes including Muckle-Wells syndrome, and many others. [2, 10] While acute urticaria is generally related to an exogenous allergen or acute infection, chronic urticaria is more likely to be associated with autoimmunity. [8, 11, 12]
She’ll also ask about the you eat and if you have pets, to see if an allergy is to blame. She may check for other illnesses or conditions that could be causing the hives, like an overactive or underactive thyroid.
Delayed-pressure urticaria: Application of deep pressure to the skin produces swelling after 1-5 hours, like sitting on one spot for a prolonged period of time. The area will be deep and tender to touch.
Other drugs such as Colchicine, Warfarin, Nifedipine, Dapsone, Methotrexate and Sulfasalazine have been used with some success reported in chronic urticaria. Auto-immune thyroid disease with associated urticaria may respond to oral Thyroxine supplementation even if normal thyroid function. Immune suppressive therapy such as Cyclosporin is effective but can cause serious side effects such as kidney damage and uncontrolled hypertension.  Oral Sodium Cromoglycate may benefit Food related Exercise induced Urticaria. Stress (public speaking, examinations, exercise and arguments) may trigger Cholinergic Urticaria and Propranolol will reduce symptoms.
Morbidity depends on the severity and duration of the condition. One study found that urticaria patients can have as much psychologic, social, and occupational distress as patients who are awaiting triple coronary artery bypass surgery. [28]
If hives occur with swelling of the tongue or throat, difficulty breathing or low blood pressure, anaphylaxis should be suspected. Urgent administration of adrenaline and medical assessment is required. Information about anaphylaxis is available on the ASCIA website www.allergy.org.au/anaphylaxis
The Asthma and Allergy Foundation of America (AAFA), a not-for-profit organization founded in 1953, is the leading patient organization for people with asthma and allergies, and the oldest asthma and allergy patient group in the world.
The #1 best proven method of eliminating stress hives from your life forever is to remove ALL stress and tension from your life. Aside from that, the only other way is to take an OTC medication like OxyHives that has proven to get rid of hives within 1-2 hours. OxyHives has been around for over 10 years now and is effective without any of the harmful side effects other hives medications have. OxyHives recently received approval to sell their hives treatment over the counter and thus no longer requires a prescription. Please see our hives treatment page for more information.

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