“cold urticaria natural treatment |how can you get hives”

Darius Mehregan, MD, Associate Professor, Hermann Pinkus Chairman of Dermatology, Department of Dermatology, Wayne State University School of Medicine; Clinical Associate Professor of Pathology, University of Toledo College of Medicine; Dermatopathologist, Pinkus Dermatopathology Laboratory; Consulting Staff, Department of Dermatology, J Dingell Veterans Affairs Medical Center
Making a paste of baking soda and water can help to calm hives and also prevent new ones from popping up. Baking soda is known as nahcolite, which is part of the natural mineral natron. Natron contains large amounts of sodium bicarbonate. It has been used since ancient times as a soother and cleanser. Mix a teaspoon of baking soda with some cold water to create a paste and then rub it on the affected area. Let it dry completely before washing it off. You can do this a few times a day, if needed. Relief is typically immediate from this easy hives treatment.
Information regarding history of previous urticaria and duration of rash and itching is useful for categorizing urticaria as acute, recurrent, or chronic. For chronic or recurrent urticaria, important considerations include previous causative factors and the effectiveness of various treatments, as follows [2] :
Diet plays a very important role in the treatment of urticaria, especially in the case of a food allergy. The first step in planning your diet for urticaria is to avoid the food that is causing the reaction. If you are unsure as to what food caused your reaction, you would need to make a list of all the foods that you have consumed in the last 24 hours and avoid all of them if possible. Try to recall if your diet in the last 48 hours included foods that you do not usually consume. Take away food, especially Chinese food is often associated with food allergies due to the spices and condiments that are used to prepare them. 
In some patients pressure on the skin may cause histamine release and a ‘weal and flare’ response, a condition known as dermographism (Fig. 3). There may also be a delayed response to pressure, with urticaria and/or angioedema developing several hours after a pressure stimulus [21].
Papular urticaria is rare in the first year of life. It is most common in children between the ages of 2 and 7 years, but may occur in adults. The incidence decreases with age, presumably because one gets less sensitive with each bite. Papular urticaria is frequently seasonal, especially in temperate climates where they are worst in the summer. However, it can occur throughout the year.
Acute urticaria, which is an allergic (IgE-mediated) reaction, is common in both children and adults. This type of urticaria is a self-limiting process that occurs when mast cells in the skin are activated, degranulate, and secrete histamine, leukotrienes, platelet activating factor (PAF), enzymes such as tryptase and chymase, cytokines, and chemotactic cytokines (chemokines). When an allergen (for example, a food) to which the person is allergic arrives via the bloodstream to mast cells in the skin, it binds to the IgE, and the mast cells become activated, and degranulate. Allergens that can result in acute urticaria include foods, drugs (particularly antibiotics such as penicillin), and venoms from bee, wasp, yellow jacket, hornet, or fire ants. Virtually any allergen that can be disseminated throughout the body, and to which there is an IgE response, has the potential to cause generalized urticaria.
In addition to this, it would be wise to stick to a bland diet for a few days or until the symptoms subside. Avoid foods like shellfish, eggs, and pineapples as they could aggravate your condition. It would also be best if you also avoid milk and milk products, eggs, and soy products.
Chronic hives can lead to severe discomfort, distress, and possibly depression. Stress, too, can aggravate hives, creating a vicious cycle. Patients who experience symptoms of depression should speak to a doctor.
Dermatographism, the ability to write on the skin, can occur as an isolated disorder that often presents as traumatically induced urticaria. It can be diagnosed by observing the skin after stroking it with a tongue depressor or fingernail (click for picture). A white line secondary to reflex vasoconstriction is followed by pruritus, erythema, and a linear wheal, as is seen in a classic wheal-and-flare reaction. It is rarely severe enough to require treatment.
A single hive generally fades in about 24 hours. But new hives may form as old hives disappear. If you have multiple hives, you may experience these symptoms for about 6 weeks. This is considered a bout of acute hives.
Individuals who have urticaria due to aspirin may need to avoid foods that contain high levels of salicylates. As well as this, antihistamines are the mainstay of drug treatment for urticaria and angioedema. They may be taken just when required or regularly to prevent episodes occurring in chronic spontaneous urticaria.
In so many words, stress hives are caused by excessive stress. When you’re stressed out, your immune system is thrown off a little bit. In an effort to try to “fix” the problem (stress), your immune system sends out histamine. It’s as if your body becomes allergic to stress.Since histamine can’t cure stress, it causes your body to develop hives instead.
Natural hives treatment can come in the form of a calming oatmeal bath. Simply add a cup or two of uncooked oats into a stocking or cheesecloth. Tie it up with a rubber band so the oats can’t leak out. Put the oats under the running water as your bath fills up. Your bath will be infused with oatmeal’s skin-calming goodness. Oats are known for their ability to calm skin inflammation, thanks to their naturally high salicylic acid content. Taking an oatmeal bath for hives can help calm these unwanted eruptions for both adults and children. Just make sure the water is warm — not too hot or too cold — since temperature extremes can just make hives worse. (17)
This is a common disorder of unknown origin, whose subjects need not be atopic individuals; that is, they do not have an increased incidence of atopic dermatitis, allergic rhinitis, or asthma compared to the incidence of these disorders in the absence of chronic urticaria although their IgE level, as a group, is higher than normal. Some patients are dermatographic, although this is usually of milder degree than is seen with the IgE-dependent dermatographism described earlier. The dermatographism may wax and wane, and the urticaria may vary from severe to mild or may intermittently subside. These individuals have a normal white-blood-cell count and erythrocyte sedimentation rate (ESR) and have no evidence of systemic disease. CSU does not appear to be an allergic reaction in the classic sense, because IgE antibody is not involved and no external allergen is needed to initiate or perpetuate the process. It differs from allergen-induced skin reactions or from physically induced urticaria (e.g., dermatographia or cold urticaria) in that histologic studies reveal a prominent cellular infiltrate around small venules, with an increased number of mast cells. External examination reveals hives with palpably elevated borders, sometimes varying greatly in size and/or shape but generally being rounded.
In a November 2008 interview with leading Swedish newspaper Dagens Nyheter, Swedish rapper Petter announced that the Hives were working on a new version of his track “Repa skivan” for his upcoming album.[24]
The band claims it was formed in 1993 (although formed in 1989 under a different name and sound) under the guidance of Randy Fitzsimmons. Fitzsimmons suggested that they form a garage rock band. He gave each band member a letter asking them to start the band. Fitzsimmons allegedly acts as a songwriter and manager for the band. The band recorded a demo titled Sounds Like Sushi in 1994. The following year they were signed to Burning Heart, a Swedish skate punk record label. The following year they released their debut EP Oh Lord! When? How? Almqvist decided to promote the band to Burning Heart.[4]
Rashes caused by stress may vary in treatment and length. Stress rash caused by hives will likely disappear with time and mild-to-moderate treatments. You may need to see a doctor to treat stress-related skin conditions such as acne, dermatitis, or severe or long-lasting hives. If you have chronic conditions like psoriasis and rosacea, you should work with your doctor to develop an appropriate treatment plan to use in the long term.
Urticaria, or hives, is a dermatologic condition that causes swollen, red bumps on the Also known as weals, these bumps usually appear rapidly and can be anywhere on the body, causing your skin to itch, burn, or sting.
Urticaria is the medical name for hives. These are welts; pink swellings that come up on any part of the skin. They itch and each individual hive lasts a few hours before fading away, leaving no trace. New hives appear as old areas fade. They can be pea sized or join to cover broad areas of the body. While the itch can be intense, the skin is usually not scabbed or broken. In some people the hives burn or sting.
^ Jump up to: a b c Griffiths, Christopher; Barker, Jonathan; Bleiker, Tanya; Chalmers, Robert; Creamer, Daniel (2016). Rook’s Textbook of Dermatology, 4 Volume Set (9 ed.). John Wiley & Sons. p. Chapter 42.3. ISBN 9781118441176.
Jump up ^ Kaplan AP (2009). “What the first 10,000 patients with chronic urticaria have taught me: a personal journey”. J Allergy Clin Immunol. 123 (3): 713–717. doi:10.1016/j.jaci.2008.10.050. PMID 19081615.
Hives (urticaria) is a common skin rash characterised by one or many weals of reddened, raised and itching skin. The weals can vary in size, from relatively small to as large as a dinner plate. The weals may be circular, oval or annular (ring-shaped).
It was during the promotion of Veni Vidi Vicious and Your New Favourite Band that the Hives signed a record deal with Universal Music, reportedly worth $50 million. This led to a dispute between the Hives and Burning Heart, who claimed that the Hives were still contracted to them for one more album.
Severe reactions can be seen with exposure to cold water; swimming in cold water is the most common cause of a severe reaction. This can cause a massive discharge of histamine, resulting in low blood pressure, fainting, shock and even loss of life. Cold urticaria is diagnosed by dabbing an ice cube against the skin of the forearm for 1 to 5 minutes. A distinct hive should develop if a patient suffers cold urticaria. This is different from the normal redness that can be seen in people without cold urticaria. Patients with cold urticaria need to learn to protect themselves from a hasty drop in body temperature. Regular antihistamines are not generally efficacious. One particular antihistamine, cyproheptadine (Periactin), has been found to be useful. The tricyclic antidepressant doxepin has also been found to be an effective blocking agent of histamine discharge. Finally, a medication named ketotifen, which keeps mast cells from discharging histamine, has also been employed with widespread success.[citation needed]
Sandalwood essential oil is effective in calming the skin and reducing itching. It cools the skin down and decreases the pain as well. Apply sandalwood oil to the rash every three to four hours for speedy results.
Heat-induced urticaria:This is a common form of chronic urticaria (5-7%). It appears as small wheals (1-2 mm in diameter), with large areas of flares around it. It frequently involves the skin of the neck and chest. It is associated with increased body temperature, e.g., after exercise, hot showers and emotional stimuli.
Other options for refractory symptoms of chronic hives include anti-inflammatory medications, omalizumab, and immunosuppressants. Potential anti-inflammatory agents include dapsone, sulfasalazine, and hydroxychloroquine. Dapsone is a sulfone antimicrobial agent and is thought to suppress prostaglandin and leukotriene activity. It is helpful in therapy-refractory cases[44] and is contraindicated in patients with G6PD deficiency. Sulfasalazine, a 5-ASA derivative, is thought to alter adenosine release and inhibit IgE mediated mast cell degranulation, Sulfasalazine is a good option for people with anemia who cannot take dapsone. Hydroxychloroquine is an antimalarial agent that suppresses T lymphocytes. It has a low cost however it takes longer than dapsone or sulfasalazine to work.
Immunological: Some hives are caused by changes in the immune system. A typical scenario would be coming in contact with something that causes cells in the immune system to trigger the release of histamine from certain white blood cells called mast cells.
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In a small percentage of patients with chronic urticaria, perhaps about 2% [71], there is an underlying small vessel vasculitis. It is important to diagnose these patients because they may have an associated systemic illness which can lead to severe complications and because the treatment of urticarial vasculitis differs from that of ordinary chronic urticaria. Clinically, the lesions of urticarial vasculitis are longer-lasting (3–7 days) than those of ordinary chronic urticaria. They are often painful or ‘burning’ and they may leave residual bruising or hyperpigmentation of the skin. Approximately 40% of patients with urticarial vasculitis will have associated angioedema. Urticarial vasculitis may occur at any age, but the median age of incidence is 43 years. Women are affected twice as often as men. Two categories of urticarial vasculitis are recognized – hypocomplementaemic and normocomplementaemic [72]. Patients with hypocomplementaemic urticarial vasculitis syndrome (HUVS) are more likely to have an associated connective tissue disease and systemic symptoms than patients with normal complement levels [73] and may have IgG antibodies to the collagen-like domain of C1q [74]. There may be associated fever, arthralgia (50%), gastrointestinal involvement with abdominal pain, nausea, vomiting and diarrhoea (20%); pulmonary disease with dyspnoea or pulmonary effusions (20%); and glomerulonephritis with haematuria and proteinuria (5–10%). Progressive renal disease is rare, unless the urticarial vasculitis is associated with SLE. Other rare manifestations include eye involvement, lymphadenopathy, splenomegaly and pericardial effusions.

“urticaria allergy what do hives look like on skin”

The Food Standards Code requires that certain foods must be listed on the package of a food, or made known to the customer upon request. If you experience an allergic reaction to a known allergen not…
Urticaria occurs when certain substances such as histamine are released from specific cells in the skin. This process is usually triggered by various immunologic mechanisms, most commonly involving the presence of circulating “IgE” antibodies, although other pathways may also be involved.
Fortunately, it’s easy to find out whether cold is one of your triggers: Your doctor can administer a simple test that involves placing an ice cube on your skin for five minutes to see if a reaction occurs. If it turns out that cold is a trigger for you, your doctor will recommend that you protect your skin from the cold and take your medications as prescribed.
Practice positive affirmations. Positive affirmations are phrases you say to yourself to help reduce your stress and bring up your mood. When saying these, use the present tense and repeat as often as you can. Examples of positive affirmations are:
Where possible, identify and treat the cause. Nonspecific aggravating factors should be minimised, such as overheating, stress, alcohol, caffeine and medication likely to cause urticaria (eg, non-steroidal anti-inflammatory drugs (NSAIDs) and angiotensin-converting enzyme (ACE) inhibitors). Topical anti-pruritic agents such as calamine lotion or topical menthol 1% in aqueous cream may help ease symptoms.
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The most common foods that cause hives are nuts, chocolate, fish, tomatoes, eggs, fresh berries, soy, wheat, and milk. Fresh foods cause hives more often than cooked foods. Certain food additives and preservatives may also be to blame.
Hives is caused by the release of histamine and other mediators of inflammation (cytokines) from cells in the skin. This process can be the result of an allergic or nonallergic reaction, differing in the eliciting mechanism of histamine release.[20]
Temperature: If you develop hives when exposed cold, do not swim alone in cold water and always carry an epinephrine auto-injector. Avoid exposure to cold air and use a scarf around your nose and mouth in cold weather. If you must be out in the cold, wear warm clothing.
If your hives are uncomfortable or disrupting your life, consider seeing an allergist or physician to determine the underlying cause, especially if you have never had hives before. In many cases, a doctor can prescribe or recommend an over-the-counter medication that can help relieve your symptoms or calm down your hives as they occur.
Jump up ^ AU Erbagci Z SO (2002). “The leukotriene receptor antagonist montelukast in the treatment of chronic idiopathic urticaria: a single-blind, placebo-controlled, crossover clinical study”. J Allergy Clin Immunol. 110 (3): 484–488. doi:10.1067/mai.2002.126676. PMID 12209099.
Angioedema is different. The swelling happens under the skin, not on the surface. It’s marked by deep swelling around the eyes and lips and sometimes of the genitals, hands, and feet. It generally lasts longer than hives, but the swelling usually goes away in less than 24 hours. It’s rare, but angioedema of the throat, tongue, or lungs can block your airways, making it hard to breathe.
Disclosure: Serve(d) as a speaker or a member of a speakers bureau for: Biogen/IDEC (Discussion of Drug reactions in relationship to an agent for Multiple Sclerosis)
Received income in an amount equal to or greater than $250 from: Abbvie; Lilly; Argenx; Amgen
Received honoraria from UpToDate for author/editor; Received honoraria from JAMA Dermatology for associate editor; Received royalty from Elsevier for book author/editor; Received dividends from trust accounts, but I do not control these accounts, and have directed our managers to divest pharmaceutical stocks as is fiscally prudent from Stock holdings in various trust accounts include some pharmaceutical companies and device makers for i inherited these trust accounts; for: Celgene; Pfizer; 3M; Johnson and Johnson; Merck; Abbott Laboratories; AbbVie; Procter and Gamble; Amgen.
You should also avoid using irritating moisturizers or lotions. When in doubt, opt for a formula that targets sensitive skin, such as these options. Applying immediately after bathing may also help soothe the itch.
In the overwhelming majority of cases it is not “something” causing the chronic hives, it is “nothing.” That is, in about 95% of chronic hives cases, the hives are “idiopathic” (a medical term that means there is no discernible cause). Because of those 5% of cases with a cause, it is worthwhile to see a physician to determine if any underlying disease is present (e.g. thyroid problems, liver problems, skin diseases, sinusitis) or if there is an allergic cause (i.e. a reaction to a drug, insect, food, etc.). This can be accomplished by a good history and physical, a few blood and urine tests and sometimes a skin biopsy. Some patients with chronic hives and elevated anti-thyroid antibodies in the blood improve when given thyroid supplement even if the thyroid function is normal.
Urticarial vasculitis carries a good prognosis, with most occurrences resolving in months to years. Urticarial vasculitis associated with hypocomplementemia is associated with a greater incidence of coexisting disease (ie, angioedema, connective-tissue disease [primarily SLE], chronic obstructive pulmonary disease).[10, 11] Mortality is rare. Some cohorts have demonstrated systemic involvement in roughly half of the patients, including musculoskeletal and ocular complications.[12]
“I’ve seen kids break out in hives from having a temper tantrum,” Dr. Li says. “Certainly, stress that’s anxiety-related can cause more itching in patients who have hives and they start to have more hives as a result of itching and scratching the existing ones.”
Clinical examination may reveal urticaria, dermographism or angioedema or signs of a connective tissue disease or urticarial vasculitis, but it is often normal. Similarly, investigations are very often normal, particularly if there is a long history of urticaria, with no obvious triggering factors and if the patient is clinically well. Recent guidelines from the British Association of Dermatologists [44] and the British Society of Allergy and Clinical Immunology [45] suggest that investigations are not needed in all patients; however, individual patients may be reassured by a series of normal results. Depending on the clinical history, tests may include: full blood count (FBC) and differential, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), routine biochemistry, glucose, thyroid function, thyroid autoantibodies, anti-nuclear antibody (ANA), immunoglobulins and protein electrophoresis, complement C3 and C4, cryoglobulins, SIgE tests, serology for infections, stool sample for ova, cysts and parasites and urine analysis (for evidence of infection or renal vasculitis). Further investigations may, of course, be required if the initial screening tests are abnormal. For example, the presence of a normochromic, normocytic anaemia, lymphopaenia and strongly positive ANA would prompt further investigations for SLE.
Cicardi M, Aberer W, Banerji A, Bas M, Bernstein JA, Bork K, Caballero T, Farkas H, Grumach A, Kaplan AP, Riedl MA, Triggiani M, Zanichelli A, Zuraw B; HAWK under the patronage of EAACI (European Academy of Allergy and Clinical Immunology). Classification, diagnosis, and approach to treatment for angioedema: consensus report from the Hereditary Angioedema International Working Group. Allergy. 2014 May;69(5):602-16. doi: 10.1111/all.12380. Epub 2014 Mar 27. PubMed PMID: 24673465.
Unfortunately there are no known specific therapies for HUV. The regime of prescription steroids and other immunosuppressive drugs aims to dampen the body’s production of anti-C1q antibodies.[3] However, this again renders the individual immunocompromised.
Health advice on severe hives: I have had severe hives for 1 week. Treating with 300mg of benadryl ea day, Doxypin 10 mg at bedtime and prednisone 40 mg. I am very concerned about being on Prednisone especially since it is not doing any good. Does pred
This list shows the foods that most often cause hives. But an allergy to foods is actually pretty rare, occurring in 1% of hives sufferers. Whether the food additives listed above actually cause hives is controversial. But many people think their hives are caused by food additives and want to try eliminating them.
Cold-induced Urticaria is a disorder in which hives occur within minutes of being exposed to the cold or appear as a result of the effects of warming. Total body exposure to cold, such as swimming in frigid water can result in a drop in blood pressure, fainting, shock and drowning.
Physical Urticaria (Inducible Urticaria) in its most simple form usually presents as linear scratches or Dermatographism.   Physical Urticaria is triggered by common physical stimuli such as heat, cold, sun exposure, vibration, exercise, deep pressure and even occasionally from water exposure (Aquagenic). The weals occur within minutes of the stimulus and disappear rapidly within an hour or two. Just to complicate matters, Physical Urticaria may occur together with Chronic Idiopathic Urticaria.  While Contact Urticaria an immediate allergy occuring after skin contact with fresh foods (potato, shellfish), pet saliva or latex and settles within a few hours.
Rosacea is another common skin condition. Depending on the type, it often causes small, red, sometimes pus-filled bumps to form on the skin. The skin can thicken in these areas. The rash typically covers the cheeks, nose, and forehead. But it can involve other areas of the face. These bumps may appear for weeks to months before disappearing and appearing again at a later time.
Acute and chronic urticaria can result in severely impaired quality of life from pruritus and associated sleeplessness, as well as anxiety and depression. The depression can be severe enough to lead to suicide in rare cases. Additionally, many of the diseases associated with chronic urticaria may cause significant morbidity and mortality.
Chronic urticaria is defined as hives, typically occurring daily, for greater than 6 weeks duration. Chronic idiopathic urticaria, which has no discernable external cause, comprises the majority of cases of chronic urticaria. Over half of all cases of chronic idiopathic urticaria are thought to occur by an autoimmune mechanism, primarily autoantibodies against the high affinity immunoglobulin E (IgE) receptor (FcεRI). Chronic urticaria is hypothesized to occur because of a predilection in the patient to develop reactions to self. Supporting this hypothesis, a strong association has been found between chronic urticaria and additional autoimmune diseases, such as thyroid disease, rheumatoid arthritis, systemic lupus erythematosus, Sjögren’s syndrome, celiac disease and type 1 diabetes, among others. Herein, we review the associations between chronic urticaria, thyroid disease, and other autoimmune disorders, as well as the implications that these correlations hold for therapeutic intervention in chronic urticaria.

“aquagenic urticaria |ferticare”

Try vinegar. There are many healing nutrients in vinegar. Pick any kind of vinegar. Pour 1 tsp of vinegar into 1 tbsp of water and stir. Using a cotton ball or napkin, apply the mixture to your hives. This will help soothe the itching.[11]
Acupuncture may help treat hives, but a systematic review published in 2016 concluded that “Acupuncture might be effective and safe for chronic urticaria in relieving symptoms, based on a low level of evidence.” The authors called for further studies to confirm findings.
Non-sedating H1 antihistamines are the mainstay of treatment. Cetirizine, loratadine and fexofenadine are usual choices. Studies comparing antihistamines are limited and so far no single antihistamine has shown itself to be superior for chronic spontaneous urticaria[6]. Once symptom control has been achieved, the antihistamine should be continued for 3-6 months.
An allergic skin condition featuring itchy, raised, pink areas surrounded by pale skin. These patches persist for periods of half an hour to several days and then resolve. Urticaria may result from sunlight, cold, food or drug allergy, insect bites, scabies, jelly fish stings or contact with plants. Treatment is with antihistamine drugs or corticosteroids. Also known popularly as nettle rash or hives.
A much rarer type of urticaria, known as urticaria vasculitis, can cause blood vessels inside the skin to become inflamed. In these cases, the weals last longer than 24 hours, are more painful, and can leave a bruise.
No. Seriously, stress is a mental state. And we treat mental problems with mind treatment, not with supplements. This advice, unfortunately, fails to find and explain the real cause of your stress problem.
Up to 20% of people will develop hives at some time during their life.  In most cases, hives are not due to allergy. Underneath the lining of the skin and other body organs (including the stomach, lungs, nose and eyes) are mast cells. Mast cells contain chemicals including histamine. When these are released into the skin they irritate nerve endings to cause local itch and irritation and make local blood vessels expand and leak fluid, triggering redness and swelling.
Urticaria is due to activation of mast cells in the skin, resulting in the release of histamine and other mediators. These chemicals cause capillary leakage, which causes the swelling of the skin, and vasodilation causing the erythematous reaction. There may be a trigger identified which causes this release but often the cause is not identifiable, particularly in chronic urticaria. An autoimmune reaction is thought to be involved in many such cases.
Lancey RA, Schaefer OP, McCormick MJ. Coronary artery bypass grafting and aortic valve replacement with cold cardioplegia in a patient with cold-induced urticaria. Ann Allergy Asthma Immunol. 2004 Feb. 92(2):273-5. [Medline].
In this study 5 persons reported with lice and fleas (same species of parasites had been collected from the pigeons nest) and all of them had in their head and allergic urticarial reaction, Haag wackermagel (2004) has reported concerns a married couple who were repeatedly invaded by pigeon fleas (Ceratophyllus columbae) over a period of 2 months.
There are other rashes that may look like hives, but the fact that they remain stable and do not resolve within 24 hours is helpful in distinguishing them from hives. Such rashes may need to have a small specimen of skin removed and examined under the microscope (biopsy) to accurately determine the nature of the skin disease.
Apply calamine lotion. Calamine lotion is a mixture of zinc oxide and zinc carbonate. It can be applied to hives to relieve the itching as often as needed. When the itching subsides or you want to reapply, rinse off the calamine lotion with cool water.[13]
Kids with bad allergies should carry an injectable shot of epinephrine to prevent life-threatening allergy attacks. If your child is at risk, the doctor will teach you and your child how to safely give an injection in the event of a severe allergic reaction.
“My allergist tested me for everything but we still couldn’t figure out a cause for the hives. It was so frustrating to keep searching for a cause. And as much as I was seeking answers, I wasn’t getting any, and wasn’t getting any relief either. Weeks passed, but the hives didn’t. Friends and family offered suggestions and their own explanations but they didn’t understand what I was going through.
Today, more research is being conducted on the connections between urticaria and stress. For example, some research is focusing on the relationship between stressful life events and the onset or exacerbation of chronic idiopathic urticaria; others are looking at ways to improve chronic urticaria using hypnosis and relaxation techniques. And new research is even looking at the relationship between post-traumatic stress disorder and the incidence and severity of chronic idiopathic urticaria.
When my son came in contact with caterpillars he would break out in giant hives all over his body. THANK GOD FOR THE SASAFRASS TREE!!! I would make him a cup of tea and within 30 minutes the hives disappeared completely when Benadryl never did. Can be bought at your local grocers.
Non-sedating antihistamines that block the histamine H1 receptors are the first line of therapy. First generation antihistamines such as diphenhydramine or hydroxyzine block both central and peripheral H1 receptors and can be sedating. Second generation antihistamines such as loratadine, cetirizine, or desloratadine selectively antagonize the peripheral H1 receptors and are less sedating, less anticholinergic, and generally preferred over the first generation antihistamines.[39][40]
The patients’ age, gender, use of medications, and duration of the disease were recorded, and a dermatologist also examined them to determine the possible causes of urticaria, such as drugs, food, insect bites, or other causative factors.
Jump up ^ Phan, NQ; Bernhard, JD; Luger, TA; Ständer, S (October 2010). “Antipruritic treatment with systemic μ-opioid receptor antagonists: a review”. Journal of the American Academy of Dermatology. 63 (4): 680–8. doi:10.1016/j.jaad.2009.08.052. PMID 20462660.
HUVS is a very rare and severe form of Urticarial Vasculitis. HUVS patients have more extensive complement abnormalities (low circulating 3rd and 4th complement components). As well as the symptoms of HUV, patients will suffer from systemic problems such as: episcleritis or uveitis (bloodshot or inflamed eyes) (found in 30 per cent of patients); mild glomerulonephritis (kidney disease); pleuritis (inflammation of the membrane surrounding the lungs); angioedema (swelling of the tissues under the skin) (found in 50 per cent of patients); Chronic Obstructive Pulmonary Disease (COPD) (breathing difficulties) (found in 50 per cent of patients), and cardiac involvement such as myocardial infarction (heart attack)
Physical Urticaria (Inducible Urticaria) in its most simple form usually presents as linear scratches or Dermatographism.   Physical Urticaria is triggered by common physical stimuli such as heat, cold, sun exposure, vibration, exercise, deep pressure and even occasionally from water exposure (Aquagenic). The weals occur within minutes of the stimulus and disappear rapidly within an hour or two. Just to complicate matters, Physical Urticaria may occur together with Chronic Idiopathic Urticaria.  While Contact Urticaria an immediate allergy occuring after skin contact with fresh foods (potato, shellfish), pet saliva or latex and settles within a few hours.
If you’re wondering how to get rid of your hives at home, then we can help. We’ve created a special Top 10 Best Ways To Get Rid Of Your Hives list that is going to be exactly what you need to determine what is causing your hives and how to stop them quickly and at home with natural remedies.
Special diets appear to have a limited role to play in the management of hives. Unfortunately, it is difficult to predict who will or will not respond to diet on the basis of history or allergy testing. A temporary elimination diet under close medical supervision, followed by challenges may be useful in a small number of cases. 
Your doctor may prescribe a cream or antihistamines to help with the itching. Good skin care is essential for prevention of an infection. For isolated or minor infected lesions, an antiseptic e.g. betadine can be applied. However, antibiotics may be necessary for severe or extensive infection.
In children, an objective trial of a low E numbers diet may be helpful, especially if the clinical history suggests that episodes of urticaria may be related to ingestion of foods which are high in E numbers.
If you are experiencing hives, don’t know the cause and they have lasted at least six weeks or more, talk to a specialist to see if you have chronic idiopathic urticaria. There may be medicines they can prescribe to help you manage your condition.
A weal (or wheal) is a superficial skin-coloured or pale skin swelling, usually surrounded by erythema (redness) that lasts anything from a few minutes to 24 hours. Usually very itchy, it may have a burning sensation.
Urticaria can occur due to allergy or even without allergy. Urticaria is not of a skin disease. It is a disease on the skin, due to altered immune system. The treatment for Urticaria has to be at the level of immune system.
^ Jump up to: a b American Academy of Allergy, Asthma, and Immunology. “Five Things Physicians and Patients Should Question” (PDF). Choosing Wisely: an initiative of the ABIM Foundation. American Academy of Allergy, Asthma, and Immunology. Archived from the original (PDF) on November 3, 2012. Retrieved August 14, 2012
Acute urticaria is the most common type. Symptoms last less than 6 weeks, and they typically affect the face and neck, fingers, toes, and the genitals of males. However, any part of the body can be affected.
Chronic spontaneous urticaria and angioedema is diagnosed when hives and swelling are present for more than six weeks and when it has been determined that an apparent protracted episode of urticaria is not the result of recurrent episodes of acute urticaria.
The autologous serum skin test is sometimes carried out in chronic spontaneous urtciaria, but its value is uncertain. It is positive if an injection of the patien’s serum under the skin causes a red weal.
It is estimated that urticaria will affect 25% of the population at some point in their lifetime. Chronic urticaria (CU) involves hives, typically occurring daily, for greater than 6 weeks duration. CU generally lasts 1 to 5 years, but can have a prolonged course beyond 5 years in roughly 14% of patients. Individuals affected by CU have reported emotional distress, feelings of isolation and fatigue in response to their condition, similar to findings in patients with ischemic heart disease. This underscores the importance of managing CU appropriately to minimize both physical and psychological impacts of this disease.
Stress hives are also known as a stress rash or as stress bumps. They develop due to chronic stress or tension, and appear as red raised areas and swollen areas on the skin that seem to suddenly appear. They cause itching most of the time, and some people report having a burning or stinging sensation wherever they appear. Learn more about how stress can cause chronic urticaria on our stress rash page.

“urticaria wheals |fruitarian diet”

Solar urticaria is a rare disorder in which urticaria develops on areas of the body which are exposed to sunlight. Itching and urticaria may develop within a few minutes and may progress to angioedema. The symptoms usually resolve in a few hours. (Polymorphic light eruption may also cause an itchy rash on sun-exposed skin, but this rash is papular or eczematous; usually starts 6–8 h after sun exposure and lasts for several days.) Very rarely, patients may develop ‘aquagenic’ urticaria where their skin has been in contact with water (irrespective of its temperature) or urticaria in response to vibration.
Hives causes can be avoided; sometimes only through trial and error. To do this, keep a journal of all the foods, medications and illnesses or activities that you or your child has prior to getting the hives. After a few cases of hives, your hives causes will be seen in the similarities between the cases. If you always get hives after being out in the direct sunlight for a few hours, your physical hives will then have a known allergen. In this way, you can avoid the allergen and be able to avoid the hives as well.
My rash ravaged my body after the prednisone ended and I drank a glass of wine…. Big mistake. I thought it was poison ivy but nothing helps. I’m getting it yearly and it follows the nerve paths so if you have some helpful guidance I will check it out.
A weal (or wheal) is a superficial skin-coloured or pale skin swelling, usually surrounded by erythema (redness) that lasts anything from a few minutes to 24 hours. Usually very itchy, it may have a burning sensation.
Jump up ^ Kaplan AP (2009). “What the first 10,000 patients with chronic urticaria have taught me: a personal journey”. J Allergy Clin Immunol. 123 (3): 713–717. doi:10.1016/j.jaci.2008.10.050. PMID 19081615.
Jump up ^ Champion, R. H.; Roberts, S. O. B.; Carpenter, R. G.; Roger, J. H. (1969). “Urticaria and Angio-Oedema”. British Journal of Dermatology. 81 (8): 588–97. doi:10.1111/j.1365-2133.1969.tb16041.x. PMID 5801331.
42. Sabroe RA, Grattan CE, Francis DM, Barr RM, Kobza BA, Greaves MW. The autologous serum skin test: a screening test for autoantibodies in chronic idiopathic urticaria. Br J Dermatol. 1999;140:446–52. [PubMed]
Where a standard dose of a non-sedating H1 antihistamine is ineffective, doses of up to four times the standard dose may be used, or another antihistamine added. Evidence for up-titrating the dose varies[7]. An additional sedating antihistamine such as chlorphenamine may be useful if itch is interfering with sleep. Avoid hydroxyzine if the person has a prolonged QT interval or risk factors for QT interval prolongation in line with recent guidance from the Medicines and Healthcare products Regulatory Agency (MHRA)[8].
The cause of most cases of urticarial vasculitis is unknown. It may be associated with a number of diseases, especially systemic lupus erythematosus, rheumatoid arthritis and Sjögren’s syndrome. Some cancers, including leukemias, colon and pancreatic, and infections like Hepatitis B and C can cause this form of vasculitis. So can some drugs, including antibiotics, ACE inhibitors used for treating high blood pressure, and certain diuretics.
Definitely! A stress rash can occur anytime you are feeling over stressed and anxious. Too much stress in your life will adversely affect your immune system which will cause it to start sending histamine to fight what is ailing you. Unfortunately, stress isn’t something that the immune system can “fight off”, so the end result is that you get stress induced hives. In essence, those itchy bumps all over your face, neck, chest, arms, legs and pretty much your whole body sometimes, are caused by stress. Learn what causes hives at http://www.hives.org/hives-causes.php
Previous studies have sought to determine the different types of stress that worsened symptoms in people with chronic hives. One study found that 16 percent of the people studied experienced a stressful event within one year before the onset or worsening of their hives.
Omalizumab, an anti-IgE antibody[9]. It is effective in 80% but requires monthly and relapse is common when it is stopped. The National Institute for Health and Care Excellence (NICE) recommends omalizumab as an add-on treatment for refractory severe chronic spontaneous urticaria[10].
Localized cold urticaria, in which only certain areas of the body urticate with cold contact, has been reported after predisposing conditions such as cold injury; it has also been reported at sites of intracutaneous allergen injections, ragweed immunotherapy, or insect bites.
A food allergy attack can last for quite a while as the allergen remains within your system and this increases the severity of the reaction. Drink plenty of fluids such as fresh fruit and vegetable juices as this will help to get rid of the allergen and reduce the recovery period.
Initially it is helpful to explain to patients what urticaria is and that very often it is not due to ‘an allergy’. They may be reassured that in nearly all cases there is no serious underlying medical problem causing the rash; that safe, effective treatments are available and that the long-term prognosis is usually good. A patient information leaflet, such as that available from the British Association of Dermatologists [48], is helpful.
Hives, which is also called urticaria, is a very itchy rash. It is sometimes caused by an infection and sometimes by an allergy to something (such as some foods), but often no cause is found. Many people get hives at some time in their life, but only a few have major trouble with it.
Antihistamines: The once-daily non-sedating antihistamines are the mainstay of current urticaria treatment, but quadrupling the normal recommended dose is often necessary to obtain symptom control (for example Cetirizine 10 to 30mg, Loratadine 10 to 30mg or Fexofenadine 180 to 540mg).  Once the urticaria is controlled, the dose can slowly be reduced.  Older sedating antihistamines such as Chlorpheniramine, Diphenhidramine or Hydroxyzine may help at night with sleep disturbance from itching.  Tolerance to antihistamines can develop and it may help to periodically rotate through different antihistamines. Ketotifen may be effective in children with its antihistamine and mast cell stabilising properties. If it is necessary to use antihistamines in pregnancy, Chlorpheniramine although sedating, is safest. Stomach ulcer treating Histamine H2 blockers such as Ranitidine or Cimetidine offer additive antihistamine effective if used with conventional antihistamine medication.
This process is caused by several mechanisms. The type I allergic IgE response is initiated by antigen-mediated IgE immune complexes that bind and cross-link Fc receptors on the surface of mast cells and basophils, thus causing degranulation with histamine release. The type II allergic response is mediated by cytotoxic T cells, causing deposits of immunoglobulins, complement, and fibrin around blood vessels. This leads to urticarial vasculitis. The type III immune-complex disease is associated with systemic lupus erythematosus and other autoimmune diseases that cause urticaria. [15]
The presence of systemic symptoms could mean the urticarial rash is not ordinary urticaria,” he said, suggesting that vasculitis, Schitzler’s syndrome, adult-onset Still’s disease, an autoinflammatory syndrome, or urticarial dermatitis could be at play.
Urticaria and Glutamine: i am suffering from urticaria for the last 6 months & i want to take Glutamine as a food supplement now . is it safe to consume glutamine while u hve problem of urticaria . will glutamine react with the allergy of urticaria?
Stress hives are indeed caused by too much stress, tension or anxiety in your life. When you expose your body to excessive stress, whether it be over a short period of time or a long period of time, your body’s immune system starts to falter. When your immune system is off kilter, it starts sending histamine into the body to fight off what is ailing you – stress. In essence, your body forms an allergic reaction to stress. Unfortunately, stress can not be eliminated with histamine, so instead, the histamine just causes hives to appear on your face, neck, chest and other parts of your body.
Known in medical terms as uriticaria, hives is a rash on the skin that is very itchy and red in color. Hives can occur anywhere on the body – from the face to the arms and legs and can vary in size from a few inches to a few millimeters. Hives could be a result of an allergic or non-allergic reaction and nearly twenty percent of children and adults develop hives at some point of time.
These types of antihistamines usually work well and do not cause drowsiness. Occasionally an older antihistamine which makes you sleepy may be useful, particularly if the itch keeps you awake at night. In this case an antihistamine such as chlorphenamine may be useful.
No. Seriously, stress is a mental state. And we treat mental problems with mind treatment, not with supplements. This advice, unfortunately, fails to find and explain the real cause of your stress problem.
A high-power view of the histology of urticarial vasculitis shows extensive fibrin deposition in the vessel walls. Surrounding the vessels is a mixed infiltrate predominately composed of neutrophils with leukocytoclasis.
Hives (urticaria) are raised, red spots on the skin that often itch. Hives are usually indicative of an allergic reaction. Hives are a common reaction in people who have allergies. A number of substances can trigger an outbreak of hives, including foods, medications, pollen, animal dander, or insect bites.
Other common causes are food, medication, chemicals such as acetone, a polymer such as latex, an viral, fungal, or bacterial infection, pet hair or dander, plants, and physical stimuli such as pressure, temperature, and sun exposure.[5]
Allergic reactions to foods such as nuts, seafood (including fish), chocolate, berries and milk common causes of ordinary hives. Viral infections, insect bites and medications can also cause ordinary hives.
Hives can be caused from allergens as well as physical and environmental factors such as stress, heat, sunlight or water. Untreated, the symptoms can last from a couple hours up to six weeks. As we’ll see throughout this article, many skin disorders share these causes and triggers, so close attention to detail is key when figuring out the mystery of your skin disorder.
“Chronic idiopathic hives are itchy red welts that persist for at least six weeks and have no known cause,” says Miriam Anand, MD, an allergist with Allergy Associates and Asthma in Tempe, Arizona. The condition is marked by periods of exacerbation and remission, and for many who have it, the hives may persist for more than five years.
How do you get hives? Hives are not something you can “catch” from anyone. Rather, they are your body’s response to something it ingests or experiences. The cause of hives can be a certain food, drug, infection or stress. You might be surprised to learn that stress is one of the most common causes of acute hives, along with allergies and infectious causes. Hives can literally occur at any age and appear anywhere on the body. It is estimated that one in every five people will be affected by a hives outbreak at some point in his or her life. (2)

“idiopathic hives +hives reaction”

Bluestein HM, Hoover TA, Banerji AS, Camargo CA Jr, Reshef A, Herscu P. Angiotensin-converting enzyme inhibitor-induced angioedema in a community hospital emergency department. Ann Allergy Asthma Immunol. 2009 Dec. 103(6):502-7. [Medline].
Konstantinou GN, Asero R, Ferrer M, Knol EF, Maurer M, Raap U, et al. EAACI taskforce position paper: evidence for autoimmune urticaria and proposal for defining diagnostic criteria. Allergy. 2012 Nov 15. [Medline].
37. Sabroe RA, Fiebiger E, Francis DM, et al. Classification of anti-FcepsilonRI and anti-IgE autoantibodies in chronic idiopathic urticaria and correlation with disease severity. J Allergy Clin Immunol. 2002;110:492–9. [PubMed]
Living with any long-term condition can be difficult. Chronic urticaria can have a considerable negative impact on a person’s mood and quality of life. Living with itchy skin can be particularly upsetting.
Urticarial vasculitis carries a good prognosis, with most occurrences resolving in months to years. Urticarial vasculitis associated with hypocomplementemia is associated with a greater incidence of coexisting disease (ie, angioedema, connective-tissue disease [primarily SLE], chronic obstructive pulmonary disease).[10, 11] Mortality is rare. Some cohorts have demonstrated systemic involvement in roughly half of the patients, including musculoskeletal and ocular complications.[12]
papular urticaria (urticaria papulo´sa) an allergic reaction to the bite of various insects, appearance of lesions that evolve into inflammatory, increasingly hard, red or brownish, persistent papules.
The most common foods that cause hives are nuts, chocolate, fish, tomatoes, eggs, fresh berries, and milk. Fresh foods cause hives more often than cooked foods. Certain food additives and preservatives may also be to blame.
Further investigation may find associated diseases. Laboratory studies may include renal function and immunological status. Chest x-ray should be performed in patients with hypocomplementaemia and breathing problems.
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Other options for refractory symptoms of chronic hives include anti-inflammatory medications, omalizumab, and immunosuppressants. Potential anti-inflammatory agents include dapsone, sulfasalazine, and hydroxychloroquine. Dapsone is a sulfone antimicrobial agent and is thought to suppress prostaglandin and leukotriene activity. It is helpful in therapy-refractory cases[44] and is contraindicated in patients with G6PD deficiency. Sulfasalazine, a 5-ASA derivative, is thought to alter adenosine release and inhibit IgE mediated mast cell degranulation, Sulfasalazine is a good option for people with anemia who cannot take dapsone. Hydroxychloroquine is an antimalarial agent that suppresses T lymphocytes. It has a low cost however it takes longer than dapsone or sulfasalazine to work.
73. Saigal K, Valencia IC, Cohen J, Kerdel FA. Hypocomplementemic urticarial vasculitis with angioedema, a rare presentation of systemic lupus erythematosus: rapid response to rituximab. J Am Acad Dermatol. 2003;49:S283–5. Suppl. [PubMed]
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Topical therapies for hives are available but are generally ineffective. They include creams and lotions which help numb nerve endings and reduce itching. Some ingredients which can accomplish this are camphor, menthol, diphenhydramine, and pramoxine. Many of these topical preparations require no prescription. Cortisone-containing creams (steroids), even strong ones requiring a prescription, are not very helpful in controlling the itch of hives.
There are many causes of hives including foods, drugs, infections, and diseases. Oddly enough, even though there are many potential causes, in the majority of cases of hives, the cause is unknown. Hives causes can be broken down into 3 broad groups:
The type I allergic immunoglobulin (Ig) E response is initiated by antigen-mediated IgE immune complexes that bind and cross-link Fc receptors on the surface of mast cells and basophils, thus causing degranulation with histamine release.
Researchers have identified many – but not all – of the factors that can cause hives. These include food and other substances you take, such as medications. Some people develop hives just by touching certain items. Some illnesses also cause hives. Here are a few of the most common causes:
All songwriting except covers on the band’s albums are credited to “Randy Fitzsimmons”. The band claim Fitzsimmons is an honorary “sixth Hive,” who along with writing their music, discovered and manages the band. Randy Fitzsimmons is a registered pseudonym for Niklas Almqvist [25].
After seeing the video for “Hate to Say I Told You So” on German TV, Alan McGee (Oasis, Creation Records) decided to sign the band to his newly formed Poptones label. Poptones released the ‘best of’ compilation Your New Favourite Band in 2001, which proved to be their breakthrough record, reaching No. 7 in the UK album charts. Following the success of the album, the band re-released singles “Hate to Say I Told You So” and “Main Offender” which reach numbers No. 23 and No. 24 respectively in the UK Singles chart. The band also re-released Veni Vidi Vicious in the US. “The Hives – Introduce the Metric System in Time” was included on the punk rock sampler album Punk-O-Rama Volume 5 from Epitaph Records.[6]
I have had urticaria for 7 years, and in that time I’ve made some discoveries. First, upon the first sensations of an itch, DO NOT SCRATCH IT; slap it instead. If that doesn’t work, I’ve found that a bath in the hottest water possible really helps to releive my discomfort/itch, then put on a long-sleeved cotton shirt that is relatively form-fitting (but not constrictive) and cotton yoga pants. I’ve noticed a link between my consumption of peanuts/peanut butter, coffee, and, yes, even chocolate to uriticaria outbreaks. Since I’ve eliminated peanuts/peanut butter from my diet entirely, I almost never get outbreaks (except the rare days that I have a cup of coffee as a special treat–then I know what I’m in for). Try experimenting with your diet, but I know the above mentioned foods are known to be common allergy-producing foods, so this could be a good starting (and perhaps ending) point… Good luck!

“multivariate testing |fruitarianism”

Severe chronic urticaria sometimes requires a trial of medicines which reduce inflammation, often called immune modulators or immunosuppressive medications. Recurrent courses of cortisone/steroid tablets need to be avoided due to a significant risk of side effects.
The most popular treatment for relief from hives is an over-the-counter medication that contains antihistamine. These drugs help fight against an attack of hives and counter the release of histamine from the skin cells that causes the rash. However, antihistamines tend to have side effects such as drowsiness, especially in children. If you prefer an alternative hives treatment, there are several home remedies for hives that are not only effective but safe as well. Do keep in mind that not all home remedies are subjected to scientific testing and results can therefore vary considerably. Some popular methods of home treatment for relief include:
Pityriasis rosea typically fades without treatment in six to eight weeks. During this time, you can use an OTC anti-itch medication, like diphenhydramine (Benadryl) or cetirizine (Zyrtec) to ease your symptoms.
Initially it is helpful to explain to patients what urticaria is and that very often it is not due to ‘an allergy’. They may be reassured that in nearly all cases there is no serious underlying medical problem causing the rash; that safe, effective treatments are available and that the long-term prognosis is usually good. A patient information leaflet, such as that available from the British Association of Dermatologists [48], is helpful.
Chronic infections such as viral hepatitis, sinus infections (sinusitis), and urinary tract infections can cause chronic hives. An infection with Helicobacter pylori, a bacteria commonly connected with stomach ulcers, is also associated with chronic hives. 
An allergy skin test helps identify triggers for one’s allergic reactions. Small amounts of allergy-provoking substances (allergens) are scratched into the skin. Redness and swelling develop if one allergic to the substance. A positive allergy skin test implies that the person has an IgE antibody response to that substance. The test is rapid, simple, and relatively safe.
Drugs that can cause hives and angioedema include aspirin and other nonsteroidal anti-inflammatory medications such as ibuprofen, high blood pressure drugs (ACE inhibitors), or painkillers such as codeine.
Urticaria, or hives, is a dermatologic condition that causes swollen, red bumps on the skin. Also known as weals, these bumps usually appear rapidly and can be anywhere on the body, causing your skin to itch, burn, or sting.
In 50% of patients with acute urticaria, a specific etiology can be identified. Brief episodes of urticaria can be associated with identifiable causes, and the method of exposure (ie, direct contact, oral or intravenous routes) is usually known. Urticaria is often associated with a recent infection.
Chronic idiopathic urticaria is the most common type of CU, comprising up to 90% of all cases of CU. It has been estimated that chronic idiopathic urticaria will affect between 0.6% to 5% of the population during their lifetime. Over half of all cases of chronic idiopathic urticaria are thought to be caused by an autoimmune mechanism. This is supported by the observation that 60% of patients with chronic idiopathic urticaria will have a wheal and flare reaction to intradermal autologous serum injections in the autologous serum skin test (ASST). Approximately 50% of patients with chronic idiopathic urticaria have IgG antibodies that are specific for the high affinity IgE receptor (FcεRI). These autoantibodies activate mast cells in the skin, circulating basophils, and the complement system.  Additional immunological abnormalities described to play a causative role in CU include IgG antibodies directed against IgE antibodies and the low affinity IgE receptor (FcεRII), antiendothelial antibodies, and complement C8 alpha-gamma (C8α-γ) deficiency.
73. Saigal K, Valencia IC, Cohen J, Kerdel FA. Hypocomplementemic urticarial vasculitis with angioedema, a rare presentation of systemic lupus erythematosus: rapid response to rituximab. J Am Acad Dermatol. 2003;49:S283–5. Suppl. [PubMed]
Interactions between the central nervous system and the immune system are complex and bidirectional, and there is evidence supporting an intimate structural and functional relationship between peripheral nerves and mast cells, as well as for the local secretion of mast cell influencing neuropeptides by nerves, Dr. Howard says. In the subset of patients who are termed stress responders, increased histamine release mediated by neuropeptides can be seen.
^ Jump up to: a b c Griffiths, Christopher; Barker, Jonathan; Bleiker, Tanya; Chalmers, Robert; Creamer, Daniel (2016). Rook’s Textbook of Dermatology, 4 Volume Set (9 ed.). John Wiley & Sons. p. Chapter 42.3. ISBN 9781118441176.
Antileukotrienes (eg, montelukast), which may provide additional benefit in some selected patients when combined with an H1 antihistamine; there is little evidence that they are effective as monotherapy.
Applying a cold compress to the affected areas of skin can offer some relief from pain and itching. Cooling the skin can decrease the swelling and reduce the histamine content in the bloodstream. Avoid hot baths and showers during an attack of hives as this dilates blood vessels and increases the skin flare up. Stay away from direct sunlight as well as this can aggravate a hives attack.
Angioedema is a reaction similar to hives that affects deeper layers of your skin. It most commonly appears around your eyes, cheeks or lips. Angioedema and hives can occur separately or at the same time.
Nonthrombocytopenic purpura: Cryofibrinogenemic purpura Drug-induced purpura Food-induced purpura IgA vasculitis Obstructive purpura Orthostatic purpura Purpura fulminans Purpura secondary to clotting disorders Purpuric agave dermatitis Pigmentary purpuric eruptions Solar purpura Traumatic purpura Waldenström hyperglobulinemic purpura Painful bruising syndrome
Using methods such as deep breathing, yoga, meditation and mindfulness techniques can increase your ability to deal with stressful situations as well as lower your body’s reaction when stress does appear.
Jump up ^ AU Shahar E, Bergman R, Guttman-Yassky E, Pollack S (2006). “Treatment of severe chronic idiopathic urticaria with oral mycophenolate mofetil in patients not responding to antihistamines and/or corticosteroids”. SO Int J Dermatol. 45 (10): 1224–1227. doi:10.1111/j.1365-4632.2006.02655.x.
Hives usually cause itching, but may also burn or sting. They can appear anywhere on the body, including the face, lips, tongue, throat, or ears. Hives vary in size (from a pencil eraser to a dinner plate), and may join together to form larger areas known as plaques. They can last for hours, or up to one day before fading. Read more about hives (urticaria and angioedema).
If Aspirin & Salicylate intolerance is suspected then all forms of Salicylate including toothpaste, muscle rubs and peppermints should also be avoided. Aspirin sensitive individuals tolerate the newer Cyclo-oxygenase-2 selective inhibitors or COX-2 anti-inflammatory (NSAI) medications such as Celecoxib and Meloxicam.
Hives can look ugly and are unbelievably itchy, but they are not in themselves dangerous. However, if you have hives and other symptoms such as dizziness, vomiting, diarrhea, difficulty in breathing, difficulty swallowing or faintness, these are signs and symptoms of a much more serous reaction – anaphylaxis. Anaphylaxis is life-threatening! If you experience hives plus one or more of these other symptoms soon after eating or being injected with a substance that you do not usually use, OBTAIN MEDICAL HELP IMMEDIATELY.
Mast cells are like land-mines, and contain bags filled with chemicals including histamine. When these are released into the skin in small amounts, they cause itching and irritation. When large amounts are released into the skin, fluid leaks out of blood vessels, resulting in swelling of the skin (hives). 
Low blood pressure, also referred to as hypotension, is blood pressure that is so low that it causes symptoms or signs due to the low flow of blood through the arteries and veins. Some of the symptoms of low blood pressure include:
This antibiotic is available topically and as an oral medication. This medication can treat inflammation caused by hives or other skin conditions caused by bacterial infection. It’s important to take all antibiotics prescribed.
“This subset — about 30 percent of patients who have been diagnosed with idiopathic urticaria — is the group in which we most often look to psychological factors for an explanation,” she says. “Many dermatologists will agree that it is not uncommon to see chronic idiopathic urticaria arising after a major life stressor, or for patients who are most impaired by urticaria to be those with more limited stress management skills.”
The most common foods that cause hives are nuts, chocolate, fish, tomatoes, eggs, fresh berries, and milk. Fresh foods cause hives more often than cooked foods. Certain food additives and preservatives may also be to blame.
Hives (the common term for urticaria), are pink or red itchy rashes, that may appear as blotches or raised red lumps (wheals) on the skin. They range from the size of a pinhead to that of a dinner plate. When hives first start to appear, they can be mistaken for mosquito bites. Swellings usually disappear within minutes to hours in one spot, but may come and go for days or weeks at a time, sometimes longer. In most cases hives are not due to allergy and they can be effectively treated with a non-drowsy antihistamine. When hives occur most days for more than 6 weeks this is defined as chronic (ongoing) urticaria, which may require additional medication. 
/ur·ti·ca·ria/ (ur″tĭ-kar´e-ah) hives; a vascular reaction of the upper dermis marked by transient appearance of slightly elevated patches (wheals) which are redder or paler than the surrounding skin and often attended by severe itching; the exciting cause may be certain foods or drugs, infection, or emotional stress.urticar´ial
Once you know what triggers your outbreaks, limiting your exposure to these will reduce your risk of developing hives. Keep in mind though that sometimes hives appears to be spontaneous with no known trigger. 
I have heard of him before, but after watching the documentary “Last Days of Left Eye” I was turned on to the full story about Dr. Okaben He is a man who has the Cure for AIDS, Cancer, Sickle Cell, Herpes,warts,lupus, Diabetes and every kind of illness, through a whole foods vegetarian diet and natural herbs, what he calls Electric Foods. He never went to school, college or medical school but has thousands of testimonials of healing people with HIV and AIDS, Cancer and several other illnesses. Lisa “Left Eye” Lopes of TLC was cured of Herpes by him and she was so moved by his knowledge that she went on to spread the word about him in every way she could. She also opened a Cultural/Healing Center for Children in Honduras before she passed away tragically. This all inspired me that i had to contact Dr. Okaben, because i was having herpes which could not be cure but was only managed, when i contacted Dr. Okaben, he sent me some herbs which i took, and now i can tell you, i have be totally cured of Herpes, Please if you have any form of illness especially STD,hemorrhoids,Infertility,HIV etc. you can contact him on. Name: Dr. Okaben Email: dr.okabenherbalspell@gmail.com PHONE/WHATS APP : +(2349029519146)
Once it has been discovered that the anti-IgE Fc-receptor antibody is present in a patient’s blood, it is no longer necessary to look for any other cause for hives. Why this autoantibody triggers hives only intermittently is unknown. Many people with this autoantibody feel that their hives are more likely to occur when they are stressed. Some women feel that hormonal changes that occur just prior to their menstrual periods also trigger their hives. Some medications, especially aspirin, ibuprofen (Advil), or naproxsen (Aleve) are also more likely to trigger hives. However, Tylenol (acetominophen) does not usually trigger hives or swelling.

“contact urticaria -urticaria wheals”

Early lesions show a perivascular neutrophilic infiltrate involving postcapillary venules. Leukocytoclasis is present, expansion of the vessel wall occurs, and the endothelium is intact. Eosinophils may be noted early. Fibrin deposition and extravasation of red blood cells ensue.
One proposal to explain this phenomenon is that patients have an IgE autoantibody to a cold-induced skin antigen. Passive transfer (PK-testing) has been reported. Thus, sensitization might occur in the cold, and release of mediators proceeds as the cells warm. Studies to test this hypothesis have thus far been negative. High levels of IgM and IgG antibodies directed against the Fc portion of IgE have been found in patients with cold urticaria, although the clinical significance of such autoantibodies is questionable.
Medications: Topical ointments can be applied to the skin to relieve the itch. Antihistamines will reduce the itching and swelling. Cortisone drugs used as an ointment or given by mouth may be needed.
It is okay for you to get your acute urticaria treated by conventional medicine such as anti-histamines. However, if you have urticaria for some months or years, you need homeopathy. Homeopathy is an answer to chronic urticaria.
If hives are making it difficult to sleep, then it may be necessary to see a physician. This would be especially important if you are taking nonprescription antihistamines. If your hives last longer than two months, it is also likely you will benefit from visiting a physician.
Hives usually cause itching, but may also burn or sting. They can appear anywhere on the body, including the face, lips, tongue, throat, or ears. Hives vary in size (from a pencil eraser to a dinner plate), and may join together to form larger areas known as plaques. They can last for hours, or up to one day before fading.
Cold urticaria is usually idiopathic, but it may occur in patients with cold-dependent antibodies, such as cryoglobulins or cold agglutinins [15] and there is a very rare familial form of cold-induced urticaria which is dominantly inherited [16]. Patients develop itching, erythema and urticaria affecting that part of the body which has been exposed to cold. Symptoms may worsen as the exposed area is warmed. Total immersion in cold water can cause severe symptoms with hypotension and patients should be warned that swimming in cold water can be dangerous. Local heat-induced urticaria is rare [17]. Some unfortunate patients may develop urticaria on exposure to both heat and cold [18]. Generalized heat-induced urticaria or ‘cholinergic’ urticaria is caused by exercise, sweating and hot showers or baths. The term ‘cholinergic’ is used because sweat glands are innervated by cholinergic nerve fibres. The urticarial lesions are often small and intensely itchy. Very severe cholinergic urticaria may cause hypotension and therefore there may be some overlap with the clinical syndrome of exercise-induced anaphylaxis [19,20].
The immune system normally protects us by making antibodies against foreign invaders such as bacteria and viruses. These antibodies are called IgG and are often referred to as gammaglobulins. Usually, IgG is not formed to any normal body tissue but occasionally, by error, this does happen. If antibody binds to normal tissues it can cause damage to the body or create other disease symptoms. Rheumatoid arthritis is a good example of an autoimmune disease. Antibodies that react with body tissues are felt to contribute to joint swelling and pain. Many other common diseases are caused by autoimmunity such as juvenile diabetes and low thyroid disease.
“My allergist tested me for everything but we still couldn’t figure out a cause for the hives. It was so frustrating to keep searching for a cause. And as much as I was seeking I wasn’t getting any, and wasn’t getting any relief either. Weeks passed, but the hives didn’t. Friends and family offered suggestions and their own explanations but they didn’t understand what I was going through.
Severe reactions can be seen with exposure to cold water; swimming in cold water is the most common cause of a severe reaction. This can cause a massive discharge of histamine, resulting in low blood pressure, fainting, shock and even loss of life. Cold urticaria is diagnosed by dabbing an ice cube against the skin of the forearm for 1 to 5 minutes. A distinct hive should develop if a patient suffers cold urticaria. This is different from the normal redness that can be seen in people without cold urticaria. Patients with cold urticaria need to learn to protect themselves from a hasty drop in body temperature. Regular antihistamines are not generally efficacious. One particular antihistamine, cyproheptadine (Periactin), has been found to be useful. The tricyclic antidepressant doxepin has also been found to be an effective blocking agent of histamine discharge. Finally, a medication named ketotifen, which keeps mast cells from discharging histamine, has also been employed with widespread success.[citation needed]
Angioedema is a reaction similar to urticaria except there is no redness or itchiness and that it occurs in deeper tissue and is characterised by asymmetrical swelling of tissue. Angioedema is frequently associated with urticaria but the two may occur independently. Itoccurs in around 1 in 3 people with urticaria. Angioedema is not always itchy and can sometimes be painful.
Physically induced hives and/or swelling share the common property of being induced by environmental factors such as a change in temperature or by direct stimulation of the skin by pressure, stroking, vibration, or light.
Patients taking progesterone-containing oral contraceptives or hormone replacement therapy or those with cyclic urticaria that appears during the 2nd half of the menstrual cycle and resolves with menstruation
Cholinergic urticaria is a common physical urticaria that is caused by sweating. It is sometimes referred to as heat bumps, as the rash appears as very small (1-4mm) weals surrounded by bright red flares.
An eruption of itching wheals, collquially called hives, usually of systemic origin; it may be due to a state of hypersensitivity to foods or drugs, foci of infection, physical agents (heat, cold, light, friction), or psychic stimuli.
Acute urticaria is said to affect 10%-20% of the population at some time during life. It is not uncommon in childhood, but the greatest incidence appears to be in young adults (15%). Chronic urticaria occurs more frequently in mid-life, especially in women.
If hives become a chronic or long-term problem, you should ask your physician for a referral to a specialist. An allergist can test you in order to determine, if possible, the cause of your allergic reaction. These allergy tests will cover foods, plants, chemicals, insects, and insect bites.
Chronic spontaneous urticaria (click for picture) is characterized by a non-necrotizing perivascular mononuclear-cell infiltrate (CD4 positive T lymphocytes and monocytes) with variable accumulation of eosinophils, neutrophils, and mast cells (click for picture). Patients with vasculitis and urticaria appear to be a separate sub-population in whom the cause and pathogenesis of hive formation probably involves immune complexes, complement activation, anaphylatoxin formation, histamine release, and neutrophil accumulation, activation, and degranulation.
In a very small number of patients, severe, debilitating urticaria, associated possibly with airway angioedema, bronchospasm and hypotension, persists despite treatment with high-dose H1 anti-histamines; H2 anti-histamines and/or LTRA; corticosteroids; and, perhaps, dietary interventions. These patients usually have autoimmune urticaria and cyclosporin treatment has proved effective in about 65% of such patients in a randomized double-blind study [58]. Longer courses of cyclosporin may give a lengthier clinical response [59]; however, the optimum dose and length of treatment have not yet been established. Tacrolimus [60] and mycophenolate mofetil [61] have also been effective in open-label studies. Results of intravenous immunoglobulin treatment in small numbers of patients have been variable [62,63]. The current recommendation from the clinical guidelines for the use of intravenous immunoglobulin [64] is that intravenous immunoglobulin should not be used unless all other therapies have failed. If patients require immunomodulating therapies, referral to a specialist centre is recommended.
The most common food allergies in adults are shellfish and nuts. The most common food allergies in children are shellfish, nuts, eggs, wheat, and soy. One study showed Balsam of Peru, which is in many processed foods, to be the most common cause of immediate contact urticaria.[8] A less common cause is exposure to certain bacteria, such as Streptococcus species or possibly Helicobacter pylori.[9]
It was during the promotion of Veni Vidi Vicious and Your New Favourite Band that the Hives signed a record deal with Universal Music, reportedly worth $50 million. This led to a dispute between the Hives and Burning Heart, who claimed that the Hives were still contracted to them for one more album.
Jump up ^ Chung, Man Cheung; Symons, Christine; Gilliam, Jane; Kaminski, Edward R. (2010). “Stress, psychiatric co-morbidity and coping in patients with chronic idiopathic urticaria”. Psychology & Health. 25 (4): 477–90. doi:10.1080/08870440802530780. PMID 20204926.
Treatment of urticarial vasculitis is based on systemic effects of the disease, extent of cutaneous involvement, and previous response to treatment. For patients with cutaneous involvement only, antihistamines or nonsteroidal anti-inflammatory drugs (NSAIDs) may provide symptomatic relief. However, Jachiet et al report that antihistamines were therapeutically ineffective for treatment of hypocomplementemic urticarial vasculitis.[12]
When we’re exposed to a stressful situation, our bodies prepare for confrontation. This “fight or flight” response is controlled by our hormones and nervous system and dates back to prehistory, as we prepared to fight or flee our stressor.
Previous studies have sought to determine the different types of stress that worsened symptoms in people with chronic hives. One study found that 16 percent of the people studied experienced a stressful event within one year before the onset or worsening of their hives.
Drugs that have caused allergic reactions evidenced as hives include codeine, dextroamphetamine,[7] aspirin, ibuprofen, penicillin, clotrimazole, trichazole, sulfonamides, anticonvulsants, cefaclor, piracetam, vaccines, and antidiabetic drugs. The antidiabetic sulphonylurea glimepiride, in particular, has been documented to induce allergic reactions manifesting as hives. Drug-induced hives has been known to have an effect on severe cardiorespiratory failure.[medical citation needed]
Stephen C Dreskin, MD, PhD is a member of the following medical societies: American Academy of Allergy Asthma and Immunology, American Association for the Advancement of Science, American Association of Immunologists, American College of Allergy, Asthma and Immunology, Clinical Immunology Society, and Joint Council of Allergy, Asthma and Immunology
Skin prick testing may be helpful to determine if an individual is atopic and if there are any specific contact antigens, such as foods or latex, which are likely to be triggers for the urticaria. Patients often expect ‘allergy testing’ and, once again, may be reassured by negative skin test results. However, there are two potential problems when skin prick testing patients with urticaria. First, patients need to stop anti-histamine treatment (usually for 3 days) prior to having the skin testing and during this time urticarial symptoms may become very severe and may even progress to systemic reactions requiring hospital treatment. Secondly, patients with urticaria may exhibit some degree of dermographism, which can make interpretation of skin tests very difficult. SIgE testing is the alternative to skin prick testing, although it is much more costly [46].
Discovering the exact cause of chronic urticaria is often extremely difficult. If the hives occur daily, they are most likely caused by something that you are exposed to daily. In that case, it is easier to see the cause/effect relationship. Sometimes it is several hours after exposure before the itching begins. In that case, some real detective work will be needed to find the culprit. These are the things to consider in order of importance: foods, drugs, infections, inhalants, and psychological factors.
I went in some hay and got the hives on the back of my legs so close together it looked like one big red/pink spot on the back of my legs so i took 2 cold rags and put them on the back of my legs for about 8-10 minutes and TOTALLY relieved itching.
There are no routine diagnostic tests in chronic spontaneous urticaria apart from blood count and C-reactive protein (CBC, CRP), but investigations may be undertaken if an underlying disorder is suspected.
Professional Reference articles are written by UK doctors and are based on research evidence, UK and European Guidelines. They are designed for health professionals to use. You may find the Hives (Chronic Urticaria) article more useful, or one of our other health articles.
If warranted, obtain antinuclear antibody and lupus serologies. Anti-SSA and anti-SSB may be seen in patients with Sjögren syndrome. Test results for antineutrophilic cytoplasmic antibodies are generally negative, and, if they are positive, the possibility of Wegener granulomatosis or microscopic polyangiitis should be considered.

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You can usually treat mild cases of hives or angioedema at home. See your doctor if your symptoms continue for more than a few days. Seek emergency care if you feel your throat is swelling or if you’re having trouble breathing.
Hives and stress are close related. The ideal stress hives cure would be to get rid of all the stress and tension in your body, but to be honest that´s impossible. Try at least to manage your stress levels and try and get rid of some tension. Try relaxation techniques such as yoga, meditation and self hypnosis, these methods can relieve your stress rash over time.
Known in medical terms as uriticaria, hives is a rash on the skin that is very itchy and red in color. Hives can occur anywhere on the body – from the face to the arms and legs and can vary in size from a few inches to a few millimeters. Hives could be a result of an allergic or non-allergic reaction and nearly twenty percent of children and adults develop hives some point of time.
One study found that chronic urticaria can have the same negative impact as heart disease. It also found that 1 in 7 people with chronic urticaria had some sort of psychological or emotional problem, such as: 
Diseases such as systemic lupus erythematosus (SLE) and Sjögren’s syndrome may be associated with chronic urticaria, a cryoglobulin-related urticaria or urticarial vasculitis (see below). There is an increased incidence of autoimmune thyroid disease in patients with chronic urticaria, particularly those with histamine-releasing autoantibodies –‘autoimmune urticaria’ (see below) [29,30]. Patients are usually clinically euthyroid, but both hypothyroidism and hyperthyroidism [31] may present with urticaria. Although there are case reports of urticaria associated with malignancy, a study of more than 1000 patients showed no association between chronic urticaria and malignancy [32]. In contrast, urticarial vasculitis may sometimes occur in patients with lymphoproliferative disease (see below).
Other drugs such as Colchicine, Warfarin, Nifedipine, Dapsone, Methotrexate and Sulfasalazine have been used with some success reported in chronic urticaria. Auto-immune thyroid disease with associated urticaria may respond to oral Thyroxine supplementation even if normal thyroid function. Immune suppressive therapy such as Cyclosporin is effective but can cause serious side effects such as kidney damage and uncontrolled hypertension.  Oral Sodium Cromoglycate may benefit Food related Exercise induced Urticaria. Stress (public speaking, examinations, exercise and arguments) may trigger Cholinergic Urticaria and Propranolol will reduce symptoms.
Although systemic treatment is best avoided during pregnancy and breastfeeding, there have been no reports that second-generation antihistamines cause birth defects. If treatment is required, loratidine and cetirizine are currently preferred.
Urticaria predominantly affects adult females and up to 20% of the population sometime in their life.  It presents as a diffusely raised itchy wheal and flare reaction which migrates over the skin surface. All forms of Urticaria may occur in association with deeper skin swelling or angioedema and equally, angioedema may occur in isolation with no apparent urticaria (when Hereditary Angioedema (HAE) due to a deficiency of the C1 Esterase inhibitor enzyme should be suspected).
There has been a high incidence of autoantibody to thyroid glands reported among those with anti-Fc-receptor antibodies and it is suggested that yearly thyroid testing be done by the primary care physician.
A much rarer type of urticaria, known as urticaria vasculitis, can cause blood vessels inside the skin to become inflamed. In these cases, the weals last longer than 24 hours, are more painful, and can leave a bruise.
Low blood pressure, also referred to as hypotension, is blood pressure that is so low that it causes symptoms or signs due to the low flow of blood through the arteries and veins. Some of the symptoms of low blood pressure include:
Initially it is helpful to explain to patients what urticaria is and that very often it is not due to ‘an allergy’. They may be reassured that in nearly all cases there is no serious underlying medical problem causing the rash; that safe, effective treatments are available and that the long-term prognosis is usually good. A patient information leaflet, such as that available from the British Association of Dermatologists [48], is helpful.
When my son came in contact with caterpillars he would break out in giant hives all over his body. THANK GOD FOR THE SASAFRASS TREE!!! I would make him a cup of tea and within 30 minutes the hives disappeared completely when Benadryl never did. Can be bought at your local grocers.
The Asthma and Allergy Foundation of America (AAFA), a not-for-profit organization founded in 1953, is the leading patient organization for people with asthma and allergies, and the oldest asthma and allergy patient group in the world.
Applying something cool to your skin can help relieve any irritation. To do this, grab a bag of frozen veggies or wrap a handful of ice in a towel and apply to the affected area for up to 10 minutes. Repeat as needed throughout the day.
Urticaria with or without fever, polyarthralgias, polyarthritis, lymphadenopathy, proteinuria, edema, and abdominal pain within 7–10 days after parenteral administration of a biologic-based drug or substance
In a November 2008 interview with leading Swedish newspaper Dagens Nyheter, Swedish rapper Petter announced that the Hives were working on a new version of his track “Repa skivan” for his upcoming album.[24]

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“Chronic idiopathic hives are itchy red welts that persist for at least six weeks and have no known cause,” says Miriam Anand, MD, an allergist with Allergy Associates and Asthma in Tempe, Arizona. The condition is marked by periods of exacerbation and remission, and for many who have it, the hives may persist for more than five years.
Urticaria and angioedema often occur at different times or together in the same person. They occur in about 15 per cent of the population at some time or other in their lives, with women more commonly affected  than men.
Individuals who have urticaria due to aspirin may need to avoid foods that contain high levels of salicylates. As well as this, antihistamines are the mainstay of drug treatment for urticaria and angioedema. They may be taken just when required or regularly to prevent episodes occurring in chronic spontaneous urticaria.
If you are constantly worried about what causes hives then you should understand that when you expose your body to excessive stress either for a small amount of time or perhaps a long period of time your own body’s immune system sets out to falter and it starts sending histamine for the body to handle what is causing problem.
The intense discomfort may tempt you to self-medicate but this is not advisable as certain medications may aggravate your condition. It would be wise to seek medical attention as soon as possible so that you recover quickly. However, if you experience fever and/or breathing problems, you may require immediate medical attention. Make a list of all your symptoms, no matter how trivial they may seem, so that your doctor is able to make an accurate diagnosis.
Chronic hives don’t put you at any sudden risk of a serious allergic reaction (anaphylaxis). But if you do experience hives as part of a serious allergic reaction, seek emergency care. Signs and symptoms of anaphylaxis include dizziness, trouble breathing, and swelling of your lips, eyelids and tongue.
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Where a standard dose of a non-sedating H1 antihistamine is ineffective, doses of up to four times the standard dose may be used, or another antihistamine added. Evidence for up-titrating the dose varies[7]. An additional sedating antihistamine such as chlorphenamine may be useful if itch is interfering with sleep. Avoid hydroxyzine if the person has a prolonged QT interval or risk factors for QT interval prolongation in line with recent guidance from the and Healthcare products Regulatory Agency (MHRA)[8].
What is cholinergic urticaria and how is it treated? Learn about cholinergic urticaria, a rash that can appear when the body gets warm and sweats. We look at symptoms, treatment, diagnosis, and prevention. Read now
Past medical history should include a detailed allergy history, including known atopic conditions (eg, allergies, asthma, eczema) and known possible causes (eg, autoimmune disorders, cancer). All drug use should be reviewed, including OTC drugs and herbal products, specifically any agents particularly associated with urticaria (see Table: Some Causes of Urticaria). Family history should elicit any history of rheumatoid disease, autoimmune disorders, or cancer. Social history should cover any recent travel and any risk factors for transmission of infectious disease (eg, hepatitis, HIV).
Make a pineapple compress. Bromelain is an enzyme found in pineapples and can help reduce the swelling of hives. Crush some pineapple, either canned or fresh, and place it on a thin cotton towel. Pull the four corners of the towel together and tie them off with a rubber band. Place the damp, pineapple filled towel over the hives.
First off, if you think you know what caused your hives, then avoid further contact or consumption with whatever it is. If you suspect that your hives are being caused by a particular food you’re eating or a certain pet you currently have in your home, then it is a good idea to get some allergy testing done. Allergy testing can reveal your hive triggers, which you can then avoid (as much as possible) and you can greatly prevent the likelihood of another undesirable hives rash. (15) Keeping a food diary can also help a hive sufferer to pinpoint any food allergies.
Physical factors such as cold, heat, sweating, exercise, pressure, sunlight, water and vibration may all trigger urticarial reactions. The weals of physical urticarias tend to be short-lived (less than an hour), apart from those of delayed pressure urticaria, which develop over a few hours and may take up to 2 days to disappear. International standards for diagnosing physical urticarias have been proposed [14].
Acute urticaria may develop in relation to a particular stressful event and it is recognized that financial, personal or professional stress may all worsen chronic urticaria. The condition itself may be very debilitating and it reduces quality of life [36].
Acute and chronic urticaria can result in severely impaired quality of life from pruritus and associated sleeplessness, as well as anxiety and depression. The depression can be severe enough to lead to suicide in rare cases. Additionally, many of the diseases associated with chronic urticaria may cause significant morbidity and mortality.
This antibiotic is available topically and as an oral medication. This medication can treat inflammation caused by hives or other skin conditions caused by bacterial infection. It’s important to take all antibiotics prescribed.
Nonthrombocytopenic purpura: Cryofibrinogenemic purpura Drug-induced purpura Food-induced purpura IgA vasculitis Obstructive purpura Orthostatic purpura Purpura fulminans Purpura secondary to clotting disorders Purpuric agave dermatitis Pigmentary purpuric eruptions Solar purpura Traumatic purpura Waldenström hyperglobulinemic purpura Painful bruising syndrome
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If a person also has angioedema, there might be puffiness, swelling, or large bumps around the eyes, lips, hands, feet, genitals, or throat. In severe cases, swelling in the throat can cause breathing trouble and lead to a loss of consciousness.
The red welts of hives happen when mast cells in the bloodstream release the chemical histamine, which causes tiny blood vessels under the skin to leak. The fluid pools within the skin to form spots and large welts. This can happen for a number of reasons, but in many cases a cause is never identified.
Immunosuppressants used for CU include cyclosporine, tacrolimus, sirolimus, and mycophenolate. Calcineurin inhibitors, such as cyclosporine and tacrolimus, inhibit cell responsiveness to mast cell products and inhibit T cell activity. They are preferred by some experts to treat severe symptoms.[46] Sirolimus and mycophenolate have less evidence for their use in the treatment of chronic hives but reports have shown them to be efficacious.[47][48] Immunosuppressants are generally reserved as the last line of therapy for severe cases due to their potential for serious adverse effects.
AAFA provides practical information, community based services and support to people through a network of Regional Chapters, Support Groups and other Local Partners around the U.S. AAFA develops health education, organizes state and national advocacy efforts and funds research to find better treatments and cures.
If you have chronic hives, or urticaria, you probably already know that when you are under stress, your symptoms either appear or worsen. Doctors have increasingly looked to study the relationship between emotional stress and skin conditions. One study, which appeared in Dermatology Times, examined the relationship between stress and chronic hives. Josie Howard, M.D., a psychiatrist in private practice and clinical instructor of psychiatry and dermatology at the University of California, stated that, “external stressors plus cognitive, behavioral and social stressors have been shown to play a significant role in the intensity of itch.” She also explains that it is not unusual for hives to appear after a major life stressor and that those with chronic hives have “limited stress management skills.”

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Mast cells are the cells in the skin and mucous membranes that contain histamine. Release of histamine causes the allergic symptoms of hives and angioedema (swelling of large areas of the body). Itching is a common symptom when histamine is released. Anti-histamines are often prescribed to help control this symptom.
I have suffered for 2 years, intense itching from head to foot. After few types of medicines, finally homeopathy could cure me. Please make sure, the homeopath must be really well qualified to diagnose root cause. I strongly recommend homeopathy for urticaria.
The hallmark red raised welts of hives sometimes have a pale center, can appear in clusters, and can change shape and location in a matter of hours. They can be from a few millimeters wide to as big as a dinner plate, and can itch, sting, or cause a burning sensation.
Urticaria is a common condition – it is estimated that lifetime incidence of urticaria is approximately 15%, with females being affected more often than males. Both children and adults may develop urticaria, with the peak age of onset in adults being between 20 and 40 years. Urticaria is defined as ‘acute’ if it lasts for less than 6 weeks and ‘chronic’ if it lasts for more than 6 weeks. ‘Episodic’ urticaria, which occurs intermittently, but recurrently over months or years, is also recognized. Most urticarial reactions are acute and self-limiting; however, patients referred to allergy clinics usually have chronic urticaria or episodic urticaria. Histology shows oedema of the upper dermis, dilatation of blood vessels and lymphatics and a cellular infiltrate in the dermis. The nature of this cell infiltrate varies depending on the type of urticaria and the duration of the weal.
Another common form of physically induced hives is called cholinergic urticaria. This produces hundreds of small, itchy bumps. These occur within 15 minutes of exercise or physical exertion and are usually gone before a doctor can examine them. This form of hives happens more often in young people.
Asthma triggers are substances, conditions or activities that lead to symptoms of asthma.Asthma symptoms include difficulty breathing, coughing, wheezing and shortness of breath. These symptoms can…
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The most common symptoms are hives that cause itching, pain and a burning feeling. Skin patches often are red-rimmed with white centers, and unlike common hives may have petechia, or bleeding under the skin. The patches can be present for days and result in skin discoloration as they heal. Some patients may also have fevers, joint and abdominal pain, shortness of breath and swollen lymph glands. Sometimes urticarial vasculitis even causes injury to vital organs including the gut, lungs and kidneys.
Updated by: David L. Swanson, MD, Vice Chair of Medical Dermatology, Associate Professor of Dermatology, Mayo Medical School, Scottsdale, AZ. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
Urticaria is caused by vasodilation and increased permeability of capillaries of the skin due to the release by mast cells of vasoactive mediators. The mast cell degranulation is due to an immunoglobulin E–mediated reaction to allergens (e.g., foods, drugs, or drug additives), heat, cold, and, rarely, infections or emotions. Urticaria is a primary sign of local and systemic anaphylactic reactions. It affects people of all ages but is most common between the ages 20 and 40. Angioedema is frequently associated with urticaria.
The next largest group of chronic hives is those with a physical trigger (cold, scratching, heat, etc.).  The smallest group is the one of most concern. A very small proportion of patient with chronic hives have an under-lying disease that can present as hives. That is why most allergists do a screening lab evaluation for patients with chronic hives. Extensive and expensive evaluation is not necessary.
Treatment of urticarial vasculitis is based on systemic effects of the disease, extent of cutaneous involvement, and previous response to treatment. For patients with cutaneous involvement only, antihistamines or nonsteroidal anti-inflammatory drugs (NSAIDs) may provide symptomatic relief. However, Jachiet et al report that antihistamines were therapeutically ineffective for treatment of hypocomplementemic urticarial vasculitis.[12]
The intense itching can become unbearable to the point where the individual may inadvertently cause damage to the skin by scratching at the affected areas. The condition can be disturbing to parents who have never experienced it themselves, but observe it in their children. Although you may find yourself exasperated as your child continues to scratch at the skin, despite your warnings against doing so, you need to keep your calm. The intense itching can be unbearable, and even adults find it near impossible to restrain themselves. Instead of admonishing your child, , make sure that you take steps to minimize the discomfort and try to distract a child with hives so that they do not scratch the rash. In severe cases, the individual may also have a fever and may suffer from digestive distress. In most cases, the rash subsides for a couple of hours or even days before it returns. Other severe urticaria symptoms include periodic flushing, headaches, dizziness, respiratory problems, fluid retention, tongue or facial swelling and hypotension. Medical attention is essential, as if neglected, severe cases of utricaria can even cause asphyxiation, resulting in death. There are several ongoing research programs to understand the exact causes of this condition in order to increase the effectiveness of existing treatment methods.
Hives are a common skin condition and rarely require serious medical intervention. Hives have a tendency to resolve on their own, but cause discomfort and pain during an attack. In very rare cases, hives may lead to a marked drop in blood pressure and shock. This is referred to as ‘anaphylactic shock’ and requires immediate medical treatment. Hives are generally caused by an allergic reaction to certain foods, medication or insect bites. There are also some cases of hives where no specific cause is determined. In such situations, changes to diet and lifestyle may help in preventing the condition. Contrary to popular belief, hives are not caused by stress or anxiety.
Disclosure: Serve(d) as a speaker or a member of a speakers bureau for: Biogen/IDEC (Discussion of Drug reactions in relationship to an agent for Multiple Sclerosis)
Received income in an amount equal to or greater than $250 from: Abbvie; Lilly; Argenx; Amgen
Received honoraria from UpToDate for author/editor; Received honoraria from JAMA Dermatology for associate editor; Received royalty from Elsevier for book author/editor; Received dividends from trust accounts, but I do not control these accounts, and have directed our managers to divest pharmaceutical stocks as is fiscally prudent from Stock holdings in various trust accounts include some pharmaceutical companies and device makers for i inherited these trust accounts; for: Celgene; Pfizer; 3M; Johnson and Johnson; Merck; Abbott Laboratories; AbbVie; Procter and Gamble; Amgen.
Chronic hives should be evaluated by an allergist, who will ask about your and your family’s medical history, substances to which you are exposed at home and at work, exposure to pets or other animals and any medications you’ve taken recently. If you have been keeping a food diary, show it to your allergist.
Applying a cold compress to the affected areas of skin can offer some relief from pain and itching. Cooling the skin can decrease the swelling and reduce the histamine content in the bloodstream. Avoid hot baths and showers during an attack of hives as this dilates blood vessels and increases the skin flare up. Stay away from direct sunlight as well as this can aggravate a hives attack.
Chronic stress that persists for weeks or even months produces cortisol, the body’s main stress-induced hormone. When cortisol becomes elevated and remains so for awhile, it affects the cells that comprise your immune system. The immune system can’t keep infections or diseases at bay as it would do normally. Viruses or bacteria proliferate to the point where they can infect many cells, leading to symptoms and increased chance of illness.
Hives causes can be avoided; sometimes only through trial and error. To do this, keep a journal of all the foods, medications and illnesses or activities that you or your child has prior to getting the hives. After a few cases of hives, your hives causes will be seen in the similarities between the cases. If you always get hives after being out in the direct sunlight for a few hours, your physical hives will then have a known allergen. In this way, you can avoid the allergen and be able to avoid the hives as well.
Cold urticaria is usually idiopathic, but it may occur in patients with cold-dependent antibodies, such as cryoglobulins or cold agglutinins [15] and there is a very rare familial form of cold-induced urticaria which is dominantly inherited [16]. Patients develop itching, erythema and urticaria affecting that part of the body which has been exposed to cold. Symptoms may worsen as the exposed area is warmed. Total immersion in cold water can cause severe symptoms with hypotension and patients should be warned that swimming in cold water can be dangerous. Local heat-induced urticaria is rare [17]. Some unfortunate patients may develop urticaria on exposure to both heat and cold [18]. Generalized heat-induced urticaria or ‘cholinergic’ urticaria is caused by exercise, sweating and hot showers or baths. The term ‘cholinergic’ is used because sweat glands are innervated by cholinergic nerve fibres. The urticarial lesions are often small and intensely itchy. Very severe cholinergic urticaria may cause hypotension and therefore there may be some overlap with the clinical syndrome of exercise-induced anaphylaxis [19,20].
Acupuncture is another option for natural hives treatment, especially for chronic hives. It is a holistic health technique that stems from Traditional Chinese Medicine practices. Trained practitioners stimulate specific points on the body by inserting thin needles into the skin. When it comes to hives, acupuncture aims to provide immediate relief from the swelling and itching. Acupuncture also tries to get to the root of the hives, including any underlying imbalances or triggers that are causing the hives. Some common acupuncture points for hives include Spleen 10 (SP 10)  and Large Intestine 11 (LI 11).  One double-blind study placebo-controlled study treated 40 patients with chronic urticaria using either real acupuncture or “sham acupuncture” for three weeks. The subjects treated with real acupuncture experienced partial remissions of symptoms after three weeks. The effectiveness of the acupuncture treatments appeared to increase with each additional treatment. (22)
Ongoing hives lasting days at a time are almost never allergic in origin, with the exception of some cases of allergy to medicines. Stress is a very rarely the cause of hives but may make the symptoms worse. 
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The following pictures are from other people that got a rash from stress. While a stress rash is very common, it is not an incurable condition. So if you are wondering “can anxiety cause a rash?” the answer is yes, and the solution is OxyHives. If none of these pictures look like your stress related rash, please keep in mind that everyone’s rash will look differently depending on various other factors.
In patients with very severe acute urticaria, associated possibly with angioedema or systemic symptoms, a short course of oral steroids is indicated. Dose and duration of the treatment is determined by the patient’s weight and clinical response. Prolonged courses of oral steroids for chronic urticaria should be avoided whenever possible, and if long-term steroid treatment is considered necessary, the patient should be followed-up regularly and prescribed prophylactic treatment against steroid-induced osteoporosis at an early stage [56]. Oral steroids may be needed for urticarial vasculitis (see below) or severe delayed pressure urticaria.
Vital signs should note the presence of bradycardia or tachycardia and tachypnea. General examination should immediately seek any signs of respiratory distress and also note cachexia, jaundice, or agitation.
Histamine is the ligand for 2 membrane-bound receptors, the H1 and H2 receptors, which are present on many cell types. The activation of the H1 histamine receptors on endothelial and smooth muscle cells leads to increased capillary permeability. The activation of the H2 histamine receptors leads to arteriolar and venule vasodilation. [3, 4, 5] This process is caused by several mechanisms as follows:
Physical urticaria: Where the skin is affected by things like cold, heat, sun exposure, vibration, pressure, sweating and exercise. The hives may only be found where the skin was affected can appear within an hour of the exposure.
[Guideline] Zuberbier T, Asero R, Bindslev-Jensen C, Walter Canonica G, Church MK, Giménez-Arnau AM, et al. EAACI/GA(2)LEN/EDF/WAO guideline: management of urticaria. Allergy. 2009 Oct. 64(10):1427-43. [Medline].
Acupuncture may help treat hives, but a systematic review published in 2016 concluded that “Acupuncture might be effective and safe for chronic urticaria in relieving symptoms, based on a low level of evidence.” The authors called for further studies to confirm findings.
Winter is not exactly the most popular season, and with good reason for those who live with chronic hives: The cold can trigger a flare-up in some. Besides the weather, other cold-related triggers include chilly foods and swimming pools. For people who are allergic to the cold, full-body immersion in a swimming pool, in particular, can trigger a severe reaction that involves not just hives but allergic shock (anaphylaxis) and loss of consciousness.