“pregnancy urticaria urticaria and angioedema”

Other measures may be appropriate, such as continuous ECG, blood pressure and pulse oximetry monitoring; administering intravenous crystalloids if the patient is hypotensive; and administering oxygen.
The emotional impact of urticaria and its effect on quality of life should also be assessed. The Dermatology Life Quality Index (DLQI) and CU-Q2oL, a specific questionnaire for chronic urticaria, have been validated for chronic urticaria, where sleep disruption is a particular problem.
Clinical Context:  Azathioprine is a purine precursor that affects the formation of adenine and guanine. This results in impaired DNA synthesis in immunocompetent cells such as lymphocytes, which are dividing rapidly during an inflammatory process. Azathioprine has a slow onset action; it is rarely used as monotherapy.
If your GP thinks that it’s caused by an allergic reaction, you may be referred to an allergy clinic for an allergy test. However, if you’ve had urticaria most days for more than 6 weeks, it’s unlikely to be the result of an allergy.
Urticaria is a common skin disease characterised by itching weals or hives that can appear anywhere on the surface of the skin. Weals may be pinpoint in size or several inches in diameter. Most sufferers experience hives continuously or intermittently for less than six weeks, but they may last longer (when they are then called ‘chronic’). Urticaria can also be accompanied by angioedema (swelling of a deeper layer of the skin). There are several varieties of urticaria, but the most common forms are acute urticaria and chronic urticaria. Common causes of acute urticaria are infections and adverse reactions to medications and foods, whereas in chronic urticaria the cause is often unknown. Intense itching is common, and it can lead to disturbed sleep and even depression, having a serious impact on a person’s quality of life. As the face and other exposed body parts can be affected, hives and angioedema can prove embarrassing for the individual.
Kevin P Connelly, DO Clinical Assistant Professor, Department of Pediatrics, Division of General Pediatrics and Emergency Care, Virginia Commonwealth University School of Medicine; Medical Director, Paws for Health Pet Visitation Program of the Richmond SPCA; Pediatric Emergency Physician, Emergency Consultants Inc, Chippenham Medical Center
The symptoms of a stress rash include red bumps and swollen areas on your skin that seem to appear randomly. Quite often, they are incredibly itchy and can also have a prickly or burning sensation when touched. Don’t scratch them! Don’t be surprised if your stress rash appears on your face, neck and chest, as that is where I get mine. Others get them on their arms and legs. Stress hives can be as small as a pencil eraser or as BIG as a dinner plate! Often the smaller hives meld with the bigger hives to make one big messy outbreak that looks absolutely terrible. However, with the right over the counter medication, like OxyHives, you’ll be able to get rid of them in no time.
The very best way to get rid of stress hives is to remove as much stress from your life as possible. There are so many effective ways to reduce stress on a daily basis. Find what works best for you and make it a part of your routine. Exercise is always one of my stress boosters. Other great ideas for stress hives treatment, and hives treatment in general, include yoga, massage, journaling and prayer.
A complete patient history is the basis for treatment. In the history, ask for time of onset of the lesions; duration of the lesions (eg, >24 h); whether lesions are painful or burning, rather than pruritic; and the history of resolution with purpura or hyperpigmentation. Inquire about the patient’s medications, fever, arthralgia, dyspnea, abdominal pain, and symptoms of angioedema. Omalizumab has produced mixed results.[18, 19]
For example, dermatologists insist that masturbation has nothing to do with acne, but trust me – masturbate 3 times a day for 4 hours. The next day, I guarantee that you’ll have a huge pimple on your cheek. Hormonal imbalance can make matters worse. It’s a proven fact.
Hormonal causes via endocrine tumors or ovarian pathology are rare. Oral contraceptive use or changes in the menstrual cycle have been reported as a possible cause of urticaria: patients commonly report worsening of hives with the menstrual cycle. This may be hormonally mediated, and the cyclical use of analgesics should also be considered as a possible etiology.
Some doctors suggest that medications should be continued for long periods – perhaps even a month after the hives have disappeared. Again, the exception to this is the cortisone/steroid-type medications, which should only be used for short periods initially to quiet down the urticaria. Remember that one must work closely with their doctor to find a medication regimen that suppresses the hives until they resolve on their own.

“hives in children +dermatographic urticaria”

[Guideline] Zuberbier T, Asero R, Bindslev-Jensen C, Walter Canonica G, Church MK, Giménez-Arnau AM, et al. EAACI/GA(2)LEN/EDF/WAO guideline: management of urticaria. Allergy. 2009 Oct. 64(10):1427-43. [Medline].
Non-sedating antihistamines that block the histamine H1 receptors are the first line of therapy. First generation antihistamines such as diphenhydramine or hydroxyzine block both central and peripheral H1 receptors and can be sedating. Second generation antihistamines such as loratadine, cetirizine, or desloratadine selectively antagonize the peripheral H1 receptors and are less sedating, less anticholinergic, and generally preferred over the first generation antihistamines.[39][40]
According to the American Osteopathic College of Dermatology, about half the cases of chronic idiopathic hives are due to immune systems that attack the body’s own tissues (also known as autoimmunity). Thyroid disease is the most commonly reported autoimmune condition in people with chronic hives, followed by rheumatoid arthritis and type 1 diabetes. A study published in September 2013 in the European Journal of Dermatology found that celiac disease is also associated with chronic hives.
Exercise daily. Even if you only have time to take a walk, exercise helps reduce stress hormones that may cause you to feel keyed up. And remember, exercise produces epinephrine, which acts as a natural decongestant, helping you breathe better.
An alternative second-line treatment to H2 anti-histamines in patients who still have severe urticaria despite high-dose H1 anti-histamine treatment, is an LTRA such as montelukast or zafirlukast. LTRA treatment may be particularly effective if the patient is sensitive to aspirin or has a positive ASST [54]; however, urticaria does not always improve with LTRA and, very occasionally, patients notice worsening of the rash [55]– in which case they should stop the treatment. LTRA alone are not used for urticaria.
Robert A Schwartz, MD, MPH Professor and Head, Dermatology, Professor of Pathology, Pediatrics, Medicine, and Preventive Medicine and Community Health, University of Medicine and Dentistry of New Jersey-New Jersey Medical School
Antihistamines that require a prescription include cyproheptadine (Periactin), which tends to cause drowsiness. A prescription antihistamine that causes little sedation is levocetirizine (Xyzal). Sometimes physicians combine these with other types of antihistamines called H2 blockers, such as ranitidine (Zantac) and cimetidine (Tagamet). This antihistamine list is not exhaustive. Physicians individualize treatment plans to suit specific patients and modify them depending on the clinical response.
/ur·ti·ca·ria/ (ur″tĭ-kar´e-ah) hives; a vascular reaction of the upper dermis marked by transient appearance of slightly elevated patches (wheals) which are redder or paler than the surrounding skin and often attended by severe itching; the exciting cause may be certain foods or drugs, infection, or emotional stress.urticar´ial
Some people react to anything that makes them hot or sweaty with hives. This can be sunlight, exercise, hot baths, blushing or anger. These are tiny intensely itchy hives with a big red blotch around them and are called cholinergic urticarial.
To treat a type of chronic hives called CIU, which can last for 6 weeks or longer and sometimes years, the U.S. Food and Drug Administration has approved 2 medications — antihistamines and omalizumab.
Vena GA, Cassano N, Colombo D, Peruzzi E, Pigatto P. Cyclosporine in chronic idiopathic urticaria: a double-blind, randomized, placebo-controlled trial. J Am Acad Dermatol. 2006 Oct. 55(4):705-9. [Medline].
Evidence of systemic autoimmune disease, including hypothyroidism or hyperthyroidism (autoimmune thyroiditis); hepatitis, renal failure, and polyarthritis (cryoglobulinemia); malar rash, serositis, and polyarthritis (SLE); dry eyes and dry mouth (Sjögren syndrome); cutaneous ulcers or hypopigmented lesions after resolution of urticaria (urticarial vasculitis)
In addition, the mission of AAFA’s Web site is to provide online access to AAFA’s reliable, validated asthma and allergy information and tools to families, patients, parents, healthcare providers, policymakers and others.
Stress hives symptoms include red bumps and swollen areas on your skin that seem to appear almost out of nowhere. They are typically quite itchy and have been known to cause a prickly or burning sensation – especially if touched. Stress hives can appear on any part of your body (face, hands, feet, arms, etc.) and can vary in size from as small as the eraser on a pencil to as large as a dinner plate. Stress hives, like a typical hives rash, have been known to spread from place to place, and smaller areas of hives can blend together to create larger areas known as plaques. These stress hives symptoms can easily be treated with the right over the counter medication.
Allergic hives and angioedema form when, in response to histamine, blood plasma leaks out of small blood vessels in the skin. Histamine is a chemical released from specialized cells along the skin’s blood vessels.
After extensive touring, the band retreated to Fagersta to record their third album. The result was 2004’s Tyrannosaurus Hives, their first new material in four years. The album includes the hit singles “Walk Idiot Walk,” which debuted at No. 13 on the UK singles charts, “Two-Timing Touch and Broken Bones,” another top 50 hit, and “A Little More for Little You.” The tracks “B is for Brutus” and “No Pun Intended” were also featured in the games Gran Turismo 4 and SSX on Tour, respectively. In 2006, their song “Diabolic Scheme” was used in the vampire film Frostbiten, marking the first time a Hives song was used in a major motion picture. (“Hate to say I told you so” featured in the 2002 ‘Spider-man’ movie starring Tobey Maguire)
Urticarial vasculitis is a form of vasculitis that affects the skin, causing wheals or hives and/or red patches due to swelling of the small blood vessels. It has two forms: One with normal levels of proteins called complements; the other with low levels of complements; it’s called hypocomplementemic vasculitis.
Jump up ^ Hirschmann, J. V.; Lawlor, F; JS; Louback, JB; Winkelmann, RK; Greaves, MW (1987). “Cholinergic Urticaria – A Clinical and Histologic Study”. Archives of Dermatology. 123 (4): 462–7. doi:10.1001/archderm.1987.01660280064024. PMID 3827277.
Chronic spontaneous urticaria and angioedema is diagnosed when hives and swelling are present for more than six weeks and when it has been determined that an apparent protracted episode of urticaria is not the result of recurrent episodes of acute urticaria.
Wong JT, Nagy CS, Krinzman SJ, Maclean JA, Bloch KJ. Rapid oral challenge-desensitization for patients with aspirin-related urticaria-angioedema. J Allergy Clin Immunol. 2000 May. 105(5):997-1001. [Medline].
After seeing the video for “Hate to Say I Told You So” on German TV, Alan McGee (Oasis, Creation Records) decided to sign the band to his newly formed Poptones label. Poptones released the ‘best of’ compilation Your New Favourite Band in 2001, which proved to be their breakthrough record, reaching No. 7 in the UK album charts. Following the success of the album, the band re-released singles “Hate to Say I Told You So” and “Main Offender” which reach numbers No. 23 and No. 24 respectively in the UK Singles chart. The band also re-released Veni Vidi Vicious in the US. “The Hives – Introduce the Metric System in Time” was included on the punk rock sampler album Punk-O-Rama Volume 5 from Epitaph Records.[6]
After a run of Californian live shows and the two weekends at the Coachella Valley Music and Arts Festival (April 15 and April 22), the band performed on Jimmy Kimmel Live! on 23 April 2012.[21] The music video for “Go Right Ahead” was released on 9 May 2012.
Histamine is the ligand for 2 membrane-bound receptors, the H1 and H2 receptors, which are present on many cell types. The activation of the H1 histamine receptors on endothelial and smooth muscle cells leads to increased capillary permeability. The activation of the H2 histamine receptors leads to arteriolar and venule vasodilation. [3, 4, 5] This process is caused by several mechanisms as follows:
Consultation with or referral to a dermatologist, allergist, immunologist, or rheumatologist may be appropriate in selected cases, particularly in cases of complicated, recurrent, refractory, severe, or chronic urticaria. Dermatology referral is mandatory if urticarial vasculitis is suspected.
Hives can further be categorized by how long they last. Acute hives last for less than six weeks; chronic hives can last longer. In many cases, a trigger that causes acute hives is not the same as what causes chronic hives.
This antibiotic is available topically and as an oral medication. This medication can treat inflammation caused by hives or other skin conditions caused by bacterial infection. It’s important to take all antibiotics prescribed.
Leukotrienes are released from mast cells along with histamine. The medications, montelukast and zafirlukast block leukotriene receptors and can be used as add on treatment or in isolation for patients with CU. It is important to note that these medications may be more beneficial for patients with NSAID induced CU.[42][43]
The common symptoms include a raised, bumpy red rash, with the bumps often looking more like normal skin colour, that is often quite itchy. The raised areas of skin are known as weals, which often fade after a few hours but can sometimes reappear elsewhere on the body.
Another common form of physically induced hives is called cholinergic urticaria. This produces hundreds of small, itchy bumps. These occur within 15 minutes of exercise or physical exertion and are usually gone before a doctor can examine them. This form of hives happens more often in young people.
Urticarial vasculitis tends to become a chronic condition and patients should be educated about its course. For most patients, this is a disease that affects the skin, with a minority of patients developing systemic complications.

“hives _urticaria medication”

Another possible explanation for your stress hives is that due to your weakened immune system, your skin is reacting to irritants that it never had problems with before: cold, heat, soaps, shampoos, lotions, laundry detergents, certain fabrics, sunlight, etc. In fact, there are even doctors that specialize in stress hives, known as psychodermatologists. These specialists work with skin illnesses and stress, and strongly feel that emotions that have not been properly dealt with can induce a rash in patients and these deep seated emotions are the major cause of chronic hives.
Morbidity depends on the severity and duration of the condition. One study found that urticaria patients can have as much psychologic, social, and occupational distress as patients who are awaiting triple coronary artery bypass surgery. [28]
Cold-induced Urticaria is a disorder in which hives occur within minutes of being exposed to the cold or appear as a result of the effects of warming. Total body exposure to cold, such as swimming in frigid water can result in a drop in blood pressure, fainting, shock and drowning.
Further investigation may find associated diseases. Laboratory studies may include renal function and immunological status. Chest x-ray should be performed in patients with hypocomplementaemia and breathing problems.
There are two types of hives – short-lived (acute) and long-term (chronic). Neither is typically life-threatening, though any swelling in the throat or any other symptom that restricts breathing requires immediate emergency care.
Although rosacea can affect anyone, it’s most common in middle-aged women who have fair skin. There’s no cure for rosacea, so treatments focus on management techniques. This includes wearing a broad-spectrum sunscreen and moisturizing frequently.
Zuberbier T, et al. European Academy of Allergy and Clinical Immunology, Global Allergy and Asthma European Network, European Dermatology Forum, World Allergy Organization. The EAACI/GA(2) LEN/EDF/WAO Guideline for the definition, classification, diagnosis, and management of urticaria: the 2013 revision and update. Allergy. 2014 Jul. 69 (7):868-87. [Medline].
Acute urticaria, which is an allergic (IgE-mediated) reaction, is common in both children and adults. This type of urticaria is a self-limiting process that occurs when mast cells in the skin are activated, degranulate, and secrete histamine, leukotrienes, platelet activating factor (PAF), enzymes such as tryptase and chymase, cytokines, and chemotactic cytokines (chemokines). When an allergen (for example, a food) to which the person is allergic arrives via the bloodstream to mast cells in the skin, it binds to the IgE, and the mast cells become activated, and degranulate. Allergens that can result in acute urticaria include foods, drugs (particularly antibiotics such as penicillin), and venoms from bee, wasp, yellow jacket, hornet, or fire ants. Virtually any allergen that can be disseminated throughout the body, and to which there is an IgE response, has the potential to cause generalized urticaria.
Typically, acute and chronic display round or oval hives, occur over virtually any part of the body and last for hours or days. There are others forms of urticaria which show up in lines or odd shapes, appear on specific parts of the body and appear then disappear within two hours. This is urticaria which is triggered by a physical cause. There are several possible causes:
Hives (urticaria) is a common skin rash characterised by one or many weals of reddened, raised and itching skin. The weals can vary in size, from relatively small to as large as a dinner plate. The weals may be circular, oval or annular (ring-shaped).
Raynaud’s phenomenon Thromboangiitis obliterans Erythromelalgia Septic thrombophlebitis Arteriosclerosis obliterans Bier spots/Marshall–White syndrome Cholesterol embolus Reactive angioendotheliomatosis Trousseau’s syndrome
The symptoms of hives include itching in most cases, swelling of the area, red welts that look much like a mosquito bite. If you have any of these symptoms, you may have hives. Most doctors when presented with hives, will try to test to find out the allergen that is responsible for the case. If the allergen simply cannot be found, such as in cold hives, only the symptoms are treated. Many doctors will give antihistamines because histamines are released into the system and this is what causes hives to form, but these commonly given antihistamines and corticosteroids only treat symptoms, not the causes. If you or your child has a life threatening case that causes constricted breathing, epinephrine is commonly given on the spot.
Angioedema is a related condition (also from allergic and nonallergic causes), though fluid leakage is from much deeper blood vessels in the subcutaneous or submucosal layers. Individual hives that are painful, last more than 24 hours, or leave a bruise as they heal are more likely to be a more serious condition called urticarial vasculitis. Hives caused by stroking the skin (often linear in appearance) are due to a benign condition called dermatographic urticaria.
In many cases, a single attack of hives is due to an infection or virus and these go away within a few days to a few weeks. Some people get repeated attacks that occur as an allergic reaction to a variety of things (foods, most commonly nuts, chocolate, fish, tomatoes, eggs, fresh berries and milk, insect stings, and medications). In this case, they usually break out within a few hours of the exposure. Usually, the patients figure out the cause by themselves, and they never bother coming to a doctor.
Hi everyone, I’m 39 years old male and I contacted the virus in 2004. I did get bad outbreaks for a while, and used to take valtrax. I hated that medicine, so i stopped it however was having outbreaks several times a year. VERY PAINFUL. A year ago I decided to search for the herpes cure, because I too believe there is one somewhere in this world. I came across zeolite (which i tried but did not cure me) and the H2O2 protocol (ingesting 35% food grade hydrogen peroxide for 30 days, per the books written by people claiming their tests came back negative). I could only do 13 days of that because the taste of the h2o2 was making me sick. So needless to say, that did not help either. As of the past 6 months,until i saw a post in a health forum about a herbal doctor from Africa who prepares herbal cure to cure all kind of diseases and virus including ALS, MND,HIV,Epilepsy, Leukemia, Asthma, Cancer, Gonorrhea etc, at first i doubted if it was real but decided to give it a try, when i contact this herbal doctor via his email, he prepared an herpes herbal portion and sent it to me via courier service, when i received this herbal portion, he gave me step by step instructions on how to apply it, when i applied it as instructed, i was cured of this deadly disease within 7 days, I could not walk or talk understandably before but after i took the herbal cure as he instructed i regained strength in my bones and i could talk properly unlike before, I am now free from the deadly virus, all thanks to Dr. Contact this great herbal doctor via his email drnogaduherbalist@gmail.com
Most of the time, a doctor can diagnose hives just by looking at the skin. To find the cause, you may be asked questions about your child’s medical history, recent exposure to allergic triggers, and daily stressors.
If the disease is very severe large doses of Methylprednisolone or Plasmapheresis (plasma exchange) may also be given. When the disease becomes quiet less toxic drugs are used to keep control and these include: Azathioprine, Methotrexate and Mycophenolate Mofetil usually in combination with low dose prednisolone.
Hives are an unpleasant inflammatory skin condition that 20 percent of the population will experience at some point in time. Thankfully, hives typically are  not serious. With some simple natural remedies, you can calm a hives outbreak on yourself or your child quite quickly. Inexpensive, common household items like oatmeal, witch hazel and baking soda are really effective at calming the itching and redness that usually accompany hives. If your child experiences hives, you should make sure you aren’t using any harsh body care products on his or her skin. You should also avoid hot baths and tight-fitting clothes. I hope that you won’t experience hives anytime soon, but if you do, a natural hives treatment will really come in handy.
As noted above, many cases of ordinary hives are “idiopathic,” meaning no cause is known. Others may be triggered by viral infections. A few may be caused by medications, usually when they have been taken for the first time a few weeks before. (It is less likely for drugs taken continuously for long periods to cause hives but certainly not impossible.) When a medication is implicated as a cause of hives, the drug must be stopped, since testing is rarely available to confirm the cause. In most cases, drug-induced hives will go away in a few days. If a drug is stopped and the hives do not go away, this is a strong indication that the medication was not the cause of the hives.
Chronic hives don’t put you at any sudden risk of a serious allergic reaction (anaphylaxis). But if you do experience hives as part of a serious allergic reaction, seek emergency care. Signs and symptoms of anaphylaxis include dizziness, trouble breathing, and swelling of your lips, eyelids and tongue.
Professional Reference articles are written by UK doctors and are based on research evidence, UK and European Guidelines. They are designed for health professionals to use. You may find the Hives (Chronic Urticaria) article more useful, or one of our other health articles.

“hives in kids |hives with fever”

The ASCIA website is intended for use by ASCIA members, other health professionals, the general public and media. The content provided is for education, communication and information purposes only and is not intended to replace or constitute medical advice or treatments. Read more…
[Guideline] Magerl M, Borzova E, Gimrnez-Arnau A, Grattan CE, Lawlor F, Mathelier-Fusade P, et al. The definition and diagnostic testing of physical and cholinergic urticarias–EAACI/GA2LEN/EDF/UNEV consensus panel recommendations. Allergy. 2009 Dec. 64(12):1715-21. [Medline].
Understanding the mechanisms of allergy is recent — just over the past 35 to 40 years, says Marshall, who is director of the division of clinical immunology and allergy at the University of Mississippi Medical Center. While allergic diseases have both genetic and environmental components there’s still so much about allergy we don’t know.
Allergic reactions, particularly to foods and medications, are another common cause of acute hives. Allergies only cause about 5 percent to 10 percent of chronic hives cases. Pet allergies are usually to blame; pollen, mold, and dust mite allergies cause chronic hives only in rare instances.
The most common symptoms are hives that cause itching, pain and a burning feeling. Skin patches often are red-rimmed with white centers, and unlike common hives may have petechia, or bleeding under the skin. The patches can be present for days and result in skin discoloration as they heal. Some patients may also have fevers, joint and abdominal pain, shortness of breath and swollen lymph glands. Sometimes urticarial vasculitis even causes injury to vital organs including the gut, lungs and kidneys.
In addition, the mission of AAFA’s Web site is to provide online access to AAFA’s reliable, validated asthma and allergy information and tools to families, patients, parents, healthcare providers, policymakers and others.
Other forms of chronic urticaria include the physical urticarias, in which the rash is triggered by stimuli such as heat, cold, sunlight, pressure, and vibration. It is important to note that many forms of urticaria get worse with heat (such as from hot baths, exercise or wearing too much clothing) and pressure (such as around tight waistbands from clothing).
Hives (the common term for urticaria), are pink or red itchy rashes, that may appear as blotches or raised red lumps (wheals) on the skin. They range from the size of a pinhead to that of a dinner plate. When hives first start to appear, they can be mistaken for mosquito bites. Swellings usually disappear within minutes to hours in one spot, but may come and go for days or weeks at a time, sometimes longer. In most cases hives are not due to allergy and they can be effectively treated with a non-drowsy antihistamine. When hives occur most days for more than 6 weeks this is defined as chronic (ongoing) urticaria, which may require additional medication. 
In most cases urticarial vasculitis is idiopathic, but it may be associated with connective tissue diseases such as SLE or Sjögren’s syndrome; infections such as hepatitis B and C, Lyme disease and infectious mononucleosis; treatment with drugs, including ACEI, cimetidine, diltiazem, penicillins, sulphonamides and thiazides; and lymphoproliferative diseases such as mixed cryoglobulinaemia and IgM gammopathy. A specific syndrome of urticarial vasculitis and IgM gammopathy with fever, bone pain and arthralgia or arthritis –‘Schnitzler’s syndrome’ – was first described in 1972 [76,77].
MedlinePlus links to health information from the National Institutes of Health and other federal government agencies. MedlinePlus also links to health information from non-government Web sites. See our disclaimer about external links and our quality guidelines.
Health advice on severe hives: I have had severe hives for 1 week. Treating with 300mg of benadryl ea day, Doxypin 10 mg at bedtime and prednisone 40 mg. I am very concerned about being on Prednisone especially since it is not doing any good. Does pred
Symptoms of chronic urticaria usually resolve, although this can take months or several years. Most people with chronic urticaria manage with appropriate doses of non-drowsy antihistamines. People with severe symptoms interfering with quality of life may be referred to a clinical immunology/allergy specialist or dermatologist for assessment and consideration of additional medications.
Some people react to anything that makes them hot or sweaty with hives. This can be sunlight, exercise, hot baths, blushing or anger. These are tiny intensely itchy hives with a big red blotch around them and are called cholinergic urticarial.
The main treatment of all forms of urticaria in adults and in children is with an oral second-generation antihistamine chosen from the list below. If the standard dose (eg 10 mg for cetirizine) is not effective, the dose can be increased up to fourfold (eg 40 mg cetirizine daily). They are stopped when the acute urticaria has settled down. There is not thought to be any benefit from adding a second antihistamine.
See an allergist, who will try to look for triggers to your hives and may recommend medications to prevent the hives or reduce the severity of symptoms. Whether the treatment is available only by prescription or over the counter will depend on several factors, including how uncomfortable the hives are making you.
Antibodies are usually raised against foreign proteins, such as those made by a replicating virus or invading bacterium. Virus or bacteria with antibodies opsonized or “stuck” to them highlight them to other cells of the immune system for clearance.
Hives, also called urticaria, are itchy, red bumps on the skin. They typically appear as an allergic reaction to food or medication, but can also be caused from emotional stress and environmental factors. Treatment for hives includes antihistamine medication, topical lotion and lifestyle change. Roughly 15 to 20 percent of all adults will be affected by hives during their lifetime, according to healthy-skin-guide.com.
While many of us might be familiar with hives and allergic reactions in generally, many more of us are unfamiliar with exactly what causes them. Hives and angioedema form when or blood plasma, begins to leak out of the small blood vessels in the skin. Allergic reactions to certain foods, insect bights, medication or even sunlight exposure can all cause a release of histamine, but nonetheless, the root cause for many hive formations is still unknown.
“When people run, they can breathe better because epinephrine pours throughout the body,” says Berger, past president of the American College of Allergy and Immunology and author of Allergies and Asthma for Dummies.”Epinephrine is also triggered during stressful moments, which should add to better breathing — not worse!”

“xolair for urticaria _hives reaction”

Gregory J Raugi, MD, PhD, Professor, Department of Internal Medicine, Division of Dermatology, University of Washington at Seattle School of Medicine; Chief, Dermatology Section, Primary and Specialty Care Service, Veterans Administration Medical Center of Seattle
The Vasculitis Foundation is pleased to announce its Dream Big! campaign. The aim of this year-long campaign is to fast track the advances about which every person impacted by vasculitis is dreaming: faster diagnosis; better, less invasive treatments; and, ultimately, a cure for all forms of the disease. Click here to learn more!
Lancey RA, Schaefer OP, McCormick MJ. Coronary artery bypass grafting and aortic valve replacement with cold cardioplegia in a patient with cold-induced urticaria. Ann Allergy Asthma Immunol. 2004 Feb. 92(2):273-5. [Medline].
The purpose of this review is to discuss the association of CU with thyroid disease and other autoimmune diseases, as well as the implications that these associations hold for therapeutic intervention in CU.
Urticaria results from the release of histamine, bradykinin, leukotriene C4, prostaglandin D2, and other vasoactive substances from mast cells and basophils in the dermis. These substances cause extravasation of fluid into the dermis, leading to the urticarial lesion. The intense pruritus of urticaria is a result of histamine released into the dermis. Histamine is the ligand for two membrane-bound receptors, the H1 and H2 receptors, which are present on many cell types. The activation of the H1 histamine receptors on endothelial and smooth muscle cells leads to increased capillary permeability. The activation of the H2 histamine receptors leads to arteriolar and venule vasodilation. [14, 15]
Diseases and medications can also cause low blood pressure. When the flow of blood is too low to deliver enough oxygen and nutrients to vital organs such as the brain, heart, and kidneys; the organs do not function normally and may be permanently damaged.
“I’ve seen kids break out in hives from having a temper tantrum,” Dr. Li says. “Certainly, stress that’s anxiety-related can cause itching in patients who have hives and they start to have more hives as a result of itching and scratching the existing ones.”
Diagnose hives. The diagnosis of hives is generally straightforward and requires only a visual examination. If you were unable to find the allergen causing your hives on your own, your doctor can run tests when you are diagnosed to determine what causes your hives. He or she does this by performing an allergy test that test for skin reactions to a variety of substances.
A complete patient history is the basis for treatment. In the history, ask for time of onset of the lesions; duration of the lesions (eg, >24 h); whether lesions are painful or burning, rather than pruritic; and the history of resolution with purpura or hyperpigmentation. Inquire about the patient’s medications, fever, arthralgia, dyspnea, abdominal pain, and symptoms of angioedema. Omalizumab has produced mixed results.[18, 19]
Hives are a very itchy rash usually caused by an allergic reaction. Hives look like raised pink spots with pale centers on the skin. The spots range from 1/2 inch to several inches wide (hives often look like mosquito bites). The spots may be different shapes. The spots rapidly and repeatedly change in location, size, and shape. Giant hives are called angioedema. This can cause large swelling beneath the skin, especially of the face.
I bought some Sovereign Silver from a health shop in America. It is an immune builder. My Urticaria was gone I swear within THREE days. You have to buy it online here but if you haven’t tried it then please do as it may work for you as it has for me. My rash was horrendous and covered every bit of my body.
In patients with chronic idiopathic urticaria, approximately 35% will experience episodes of angioedema and 25% are positive for dermatographism. Like many autoimmune diseases, chronic idiopathic urticaria has a higher incidence in women than men, with the reported ratio of females to males ranging from 2:1 to 4:1. Numerous autoimmune conditions have been associated with chronic idiopathic urticaria, including thyroid disease, celiac disease, and rheumatoid arthritis (RA).
Interactions between the central nervous system and the immune system are complex and bidirectional, and there is evidence supporting an intimate structural and functional relationship between peripheral nerves and mast cells, as well as for the local secretion of mast cell influencing neuropeptides by nerves, Dr. Howard says. In the subset of patients who are termed stress responders, increased histamine release mediated by neuropeptides can be seen.
If you experience swelling of the lips or face, trouble breathing, or wheezing, you should seek immediate medical attention. These can be life-threatening complications, and you will likely need a shot of epinephrine for treatment.
Allergies to foods and soaps or detergents are often the first things that come to mind. While many people try to avoid these suspected triggers, they frequently find that it doesn’t help. You might be surprised to know that while allergies may be the problem, other causes are more common.
This means there is no explanation for what’s causing it. This can be difficult for some people to accept when they receive the CIU diagnosis from their doctor. Because these chronic hives symptoms come and go without a known cause, many who have been diagnosed with CIU continue to look for possible triggers for their disease. This can turn into a cycle of elimination diets, changing of detergents and other changes in addition to tests for allergies – none of which prove to be the cause of these patients’ hives.
It can be easy to mistake hives for other disorders because the allergy triggers can be difficult to find. Another problem with diagnosing hives is that the symptoms are relatively generic — red, itchy welts on your skin are a common symptom among many skin disorders.

“baby hives treatment |itchy hives all over body”

There are other medications that may be added to the antihistamines, but these non-standard therapies are not always effective. However, if the hives are not responding, they are worth a try. Examples are anti-acid pills (cimetidine, ranitidine), and sulfasalazine (anti-inflammatory antibiotics), nifedipine (a blood pressure medicine), Accolate (an asthma drug), colchicine (a drug for gout), and several others.
What do bed bug bites look like? See spider bite pictures and learn how to identify bug bites from mosquitos, bees, bed bugs, wasps, and more. See what their bites & stings look like and how to treat bug bites.
If hives are making it difficult to sleep, then it may be necessary to see a physician. This would be especially important if you are taking nonprescription antihistamines. If your hives last longer than two months, it is also likely you will benefit from visiting a physician.
Known in medical terms as uriticaria, hives is a rash on the skin that is very itchy and red in color. Hives can occur anywhere on the body – from the face to the arms and legs and can vary in size from a few inches to a few millimeters. Hives could be a result of an allergic or non-allergic reaction and nearly twenty percent of children and adults develop hives at some point of time.
This is termed scombroid food poisoning. Ingestion of free histamine released by bacterial decay in fish flesh may result in a rapid-onset, allergic-type symptom complex which includes hives. However, the hives produced by scombroid is reported not to include wheals.[21]
Angioedema, on the other hand, is usually not red or itchy, but tends to sting and burn, and can be described as “numbness.” This swelling can be severe, and if it affects a person’s ability to breathe, can be life-threatening.
Konstantinou GN, Asero R, Maurer M, Sabroe RA, Schmid-Grendelmeier P, Grattan CE. EAACI/GA(2)LEN task force consensus report: the autologous serum skin test in urticaria. Allergy. 2009 Sep. 64(9):1256-68. [Medline].
Unfortunately, stress and allergies go hand in hand, says Los Angeles-based ear, nose, and throat doctor, Murray Grossan, MD. Once the allergy season is full-blown, the combination of miserable allergy symptoms, nights of fitful sleep, and fatigue, definitely leave you in need of stress relief.
We all experience stress at some time in our lives. In small amounts, stress can help you. For example, stress might keep you alert when studying for a test, or give you a boost of adrenaline when faced with a deadline. But stress is also a warning sign that something is wrong. It can set off a number of physical, cognitive and emotional symptoms that make it more difficult to deal with a situation. When you ignore the signs of stress, it may in some cases, grow stronger and can cause you to break out in hives.
Chronic or recurrent urticaria (>6 wk) – Basic laboratory studies should include complete blood count (CBC), erythrocyte sedimentation rate (ESR), thyroid-stimulating hormone (TSH), and antinuclear antibody (ANA) [4]
“I’ve seen kids break out in hives from having a temper tantrum,” Dr. Li says. “Certainly, stress that’s anxiety-related can cause more itching in patients who have hives and they start to have more hives as a result of itching and scratching the existing ones.”
Jump up ^ “Warner Bros. Interactive Entertainment & MTV Games Announce LEGO Rock Band Full Track List” (Press release). Harmonix. 12 October 2009. Archived from the original on 18 August 2011. Retrieved 18 August 2011.
Insect bites are localised, often clustered in groups of 3–5 lesions, and they appear in crops. Bites persist for days. Close inspection reveals a central punctum. Chronic hypersensitivity to insect bites is often called papular urticaria.
An alternative second-line treatment to H2 anti-histamines in patients who still have severe urticaria despite high-dose H1 anti-histamine treatment, is an LTRA such as montelukast or zafirlukast. LTRA treatment may be particularly effective if the patient is sensitive to aspirin or has a positive ASST [54]; however, urticaria does not always improve with LTRA and, very occasionally, patients notice worsening of the rash [55]– in which case they should stop the treatment. LTRA alone are not used for urticaria.

“pictures of urticaria multivariable regression”

The Asthma and Allergy Foundation of America (AAFA), a not-for-profit organization founded in 1953, is the leading patient organization for people with asthma and allergies, and the oldest asthma and allergy patient group in the world.
Hives (AKA urticaria) is not contagious by any means. They are a skin disorder that results in red, sometimes itching patches of raised skin. The patches of skin can be small or large, and generally appear quite fast and disappear on their own within hours or days. They can be as small as a few millimeters and as large as inches, and can even join together to become large areas called plaques. When they join together all over your body, they are generally known as body hives. This form of rash is often quite itchy in nature and can burn. Learn more on our page title “Are Hives Contagious?”
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Cases of urticaria and angioedema can be acute, lasting less than 6 weeks, or chronic, lasting more than 6 weeks. The length of symptoms can often be a clue as to the cause of the symptoms. For example, the most common cause of acute urticaria and angioedema in children is viral infections.
Eileen Bailey is a freelance health writer. She is the author of Idiot’s Guide to Adult ADHD, Idiot’s Guide to Cognitive Behavioral Therapy, Essential Guide to Overcoming Obsessive Love and Essential Guide to Asperger’s Syndrome. She can be found on twitter @eileenmbaileyand on Facebook at eileenmbailey.
Cold-induced urticaria: Urticaria occurs after exposure to cold, cold objects or cold water. The urticaria is usually localised to exposed areas but sudden total body exposure, as in swimming, may cause a drop in blood pressure and can rarely be fatal.
Urticaria (hives) is a vascular reaction of the skin marked by the transient appearance of smooth, slightly elevated papules or plaques (wheals) that are erythematous and that are often attended by severe pruritus. Individual lesions resolve without scarring in several hours. Most cases of urticaria are self-limited and of short duration; the eruption rarely lasts more than several days, it but may be recurrent over weeks. Chronic urticaria is defined as urticaria with recurrent episodes lasting longer than 6 weeks).
Although sinusitis, cutaneous fungal infections, Helicobacter pylori infection, or other occult infections have been reported in the literature to cause urticaria, the data are not strongly supported. [14, 15, 16, 17, 18]
Jump up ^ Chung, Man Cheung; Symons, Christine; Gilliam, Jane; Kaminski, Edward R. (2010). “Stress, psychiatric co-morbidity and coping in patients with chronic idiopathic urticaria”. Psychology & Health. 25 (4): 477–90. doi:10.1080/08870440802530780. PMID 20204926.
The “chronic” in CIU means that symptoms last six weeks or more. CIU is an unpredictable form of chronic hives that can appear at any time with no identifiable cause. These hives may not go away for many months—or even years. CIU can be difficult to diagnose.
The prognosis in acute urticaria is excellent, with most cases resolving within days. Acute urticaria usually can be controlled using only symptomatic treatment with antihistamines. If a known triggering factor is present, avoidance is the most effective therapy. Acute urticaria causes discomfort, but it does not cause mortality, unless it is associated with angioedema involving the upper airways. [25, 26, 27] If a patient continues to be exposed to a known trigger, the condition may become chronic.
Urticaria, commonly referred to as hives, is the most frequent dermatologic disorder seen in the emergency department (ED). It appears as raised, well-circumscribed areas of erythema and edema involving the dermis and epidermis that are very pruritic. Urticaria may be acute (lasting <6 wk) or chronic (lasting >6 wk). A large variety of urticaria variants exist, including acute immunoglobulin E (IgE)–mediated urticaria, chemical-induced urticaria (non-IgE-mediated), autoimmune urticaria, cholinergic urticaria, cold urticaria, mastocytosis, periodic fever syndromes including Muckle-Wells syndrome, and many others. [2, 10] While acute urticaria is generally related to an exogenous allergen or acute infection, chronic urticaria is more likely to be associated with autoimmunity. [8, 11, 12]
Urticaria predominantly affects adult females and up to 20% of the population sometime in their life.  It presents as a diffusely raised itchy wheal and flare reaction which migrates over the skin surface. All forms of Urticaria may occur in association with deeper skin swelling or angioedema and equally, angioedema may occur in isolation with no apparent urticaria (when Hereditary Angioedema (HAE) due to a deficiency of the C1 Esterase inhibitor enzyme should be suspected).
Omalizumab, an anti-IgE antibody[9]. It is effective in 80% but requires monthly injections and relapse is common when it is stopped. The National Institute for Health and Care Excellence (NICE) recommends omalizumab as an add-on treatment for refractory severe chronic spontaneous urticaria[10].
Pityriasis rosea typically fades without treatment in six to eight weeks. During this time, you can use an OTC anti-itch medication, like diphenhydramine (Benadryl) or cetirizine (Zyrtec) to ease your symptoms.
Acute hives can be related to other infections such as strep throat, athlete’s foot, mononucleosis, and coxsackie viruses. Though they’re not viral infections, both intestinal worms and malaria can also cause urticaria.
Allergic reactions to foods such as nuts, seafood (including fish), chocolate, berries and milk common causes of ordinary hives. Viral infections, insect bites and medications can also cause ordinary hives.
The important thing is that the patient is given enough medication (antihistamines, perhaps in conjunction with other drugs) to suppress the hives. Whatever it is that controls a patients hives, should be the daily regimen, taking the drugs every day, whether or not they have the hives on any given day. The idea is that one is preventing the hives from breaking out.
Urticaria (or ‘hives’ or ‘nettle rash’) consists of blancheable, erythematous, oedematous papules or ‘weals’ (Fig. 1). These weals vary in size from 1 mm to many centimetres –‘giant urticaria’, and are usually intensely itchy. They are caused by vasoactive mediators, predominantly histamine, released from mast cells. In the vast majority of cases the weals are transient, lasting for only a few hours in any one place, but with new weals appearing in other places. This means that most urticarial rashes ‘move’ around the body – a useful pointer from the clinical history that the rash is urticarial. Urticaria is to be distinguished from ‘angioedema’, which is well-demarcated swelling, occurring within deep skin structures or in subcutaneous tissue (Fig. 2) and caused mainly by bradykinin production. Angioedema is not itchy, but may be painful. In about 50% of patients urticaria occurs alone; in about 40% of patients urticaria occurs with angioedema and in about 10% of patients angioedema occurs alone [1]. The aetiology of isolated angioedema is very often different from that of urticaria or urticaria with angioedema. The topic of isolated angioedema is to be reviewed in a further article in this series.
It is typically diagnosed when chronic hives do not appear to be associated with any other systemic disease process, and are not due to one of the physically induced urticarias. Research during the past decade suggests an association with autoimmunity in 35-45% of patients. When severe, it can be resistant to therapy and there is a 40% incidence of accompanying angioedema. Angioedema may involve the face, lips, tongue, throat, or extremities but not the larynx. The remission rate is 65% within three years, 85% within five years and 98% within ten years. A form of angioedema in the absence of hives with no identifiable cause is termed idiopathic angioedema.
Keeping a daily food diary will help you pinpoint what foods are causing an adverse reaction and resulting in an attack of hives. Foods that contain large amounts of histamine or increase the release of histamine in the skin cells include shellfish, nuts, eggs, dairy, pineapple, chocolate, wine, and beer. These trigger foods should be completely avoided until you determine what exactly is causing the allergic reaction.
The very best way to get rid of stress hives is to remove as much stress from your life as possible. There are so many effective ways to reduce stress on a daily basis. Find what works best for you and make it a part of your routine. Exercise is always one of my stress boosters. Other great ideas for stress hives treatment, and hives treatment in general, include yoga, massage, journaling and prayer.
If you suffer with allergy symptoms, you know all about the stress of having a chronic condition. Not only is it difficult to breathe with allergy symptoms, but poor sleep can lead to fatigue and problems concentrating. Allergy medicines can cause appetite changes, low energy, and even irritability. All you want is relief: from the stress, the symptoms, all of it.
Many different drugs may cause urticaria. The cyclo-oxygenase (COX)-inhibitor drugs such as aspirin [22] and NSAIDs [23] are a common cause. Opiates, including codeine, may trigger direct histamine release from mast cells [24]. Many different over-the-counter analgesics contain aspirin, NSAIDs and/or codeine and it is therefore important to be specific as to exactly which painkillers patients may or may not be able to take. These reactions are not IgE-mediated and specific IgE testing for aspirin, NSAIDs and opiates is not indicated. Evidence of oxidative damage, as shown by increased protein carbonylation and lipid peroxidation, and of increased anti-oxidant enzyme activity has been found in patients who develop non-IgE-mediated drug-related urticaria [25]; however, it is not known if this oxidative stress is the cause or the effect of the reaction. [Drugs such as angiotensin converting enzyme inhibitors (ACEI) and statins cause isolated angioedema much more commonly than urticaria]. Radio-contrast media and plasma substitutes may also cause urticarial reactions.
Jump up ^ Champion, R. H.; Roberts, S. O. B.; Carpenter, R. G.; Roger, J. H. (1969). “Urticaria and Angio-Oedema”. British Journal of Dermatology. 81 (8): 588–97. doi:10.1111/j.1365-2133.1969.tb16041.x. PMID 5801331.
Other medical conditions that can cause pruritus (usually without rash), such as diabetes mellitus, chronic renal insufficiency, primary biliary cirrhosis, or other nonurticarial dermatologic disorders
Try vinegar. There are many healing nutrients in vinegar. Pick any kind of vinegar. Pour 1 tsp of vinegar into 1 tbsp of water and stir. Using a cotton ball or napkin, apply the mixture to your hives. This will help soothe the itching.[11]
Hives, also known as urticaria, is a kind of skin rash with red, raised, itchy bumps.[1] They may also burn or sting.[2] Often the patches of rash move around.[2] Typically they last a few days and do not leave any long-lasting skin changes.[2] Fewer than 5% of cases last for more than six weeks.[2] The condition frequently recurs.[2]
Rubbing or scratching (simple dermographism). This is the most frequent cause of physical urticaria. Symptoms appear within a few minutes in the place that was rubbed or scratched and typically last less than an hour.
Question on Papular Urticaria: Is Urticaria & Papuller Urticaria the same? My 15 yr old sis is suffering from Papullar Urticaria since 2 yrs. We tried all medication including Allopathic (also Steroids), homeopathy. But no improvement. Pls suggest a remed
Urticaria is also known as ‘nettle rash’ or ‘hives’. This condition consists of wheals – spots or patches of raised red or white skin – each of which usually clears away in a few to be replaced by other fresh wheals. Urticaria is very common and affects one in five people at some point in their lives.  The more common type of urticaria rash (hives) lasts up to 24 hours, produces larger wheals and may not completely clear for several days.  It sometimes occurs together with swelling of various parts of the body (angioedema) – typically the face, hands and feet, although anywhere may be affected.
The main symptom of urticaria is a red, raised skin rash. They can appear anywhere on the body, including the face, hands, lips, tongue, throat or ears. Hives vary in size (from a pencil rubber to a dinner plate), and may join together to form larger areas known as plaques.

“urticaria pruritus +hives and swelling”

raised circular weals that look like mosquito bites – these are red on the outer rim and white in the centre, and each weal lasts for around two to four hours (rarely up to 24 hours). Weals appear in batches or clusters, and as one batch fades away as a new batch appears
Dr. Cole is board certified in dermatology. He obtained his BA degree in bacteriology, his MA degree in microbiology, and his MD at the University of California, Los Angeles. He trained in dermatology at the University of Oregon, where he completed his residency.
Symptoms of chronic urticaria usually resolve, although this can take months or several years. Most people with chronic urticaria manage with appropriate doses of non-drowsy antihistamines. People with severe symptoms interfering with quality of life may be referred to a clinical immunology/allergy specialist or dermatologist for assessment and consideration of additional medications.
Examination of bedding and the children’s play areas for insects may provide a clue to the cause. If insects are found, they must be eliminated by insect repellant or fumigation, and pets should be washed. These bugs are usually not visible to the naked eye. Hanging the bedding in the hot sun may rid these of the bedbugs.
Allergies to foods and soaps or detergents are often the first things that come to mind. While many people try to avoid these suspected triggers, they frequently find that it doesn’t help. You might be surprised to know that while allergies may be the problem, other causes are more common.
“This subset — about 30 percent of patients who have been diagnosed with idiopathic urticaria — is the group in which we most often look to psychological factors for an explanation,” she says. “Many dermatologists will agree that it is not uncommon to see chronic idiopathic urticaria arising after a major life stressor, or for patients who are most impaired by urticaria to be those with more limited stress management skills.”
My name is Mr. Manishkumar Mishra. I have started treatment of Urticaria for my child Mast Kartik Mishra(5 years age) PIN 33099. I started the treatment on 8 th August 2017, since then day by day with the medicines he is feeeling better nowadays. I have observed that there is very good improvement in Urticaria since last 2 months. I did not see any rash of urticaria.
Chronic hives don’t put you at any sudden risk of a serious allergic reaction (anaphylaxis). But if you do experience hives as part of a serious allergic reaction, seek emergency care. Signs and symptoms of anaphylaxis include dizziness, trouble breathing, and swelling of your lips, eyelids and tongue.
Abdominal examination should note any masses, hepatomegaly, splenomegaly, or tenderness. Neurologic examination should note any tremor or hyperreflexia or hyporeflexia. Musculoskeletal examination should note the presence of any inflamed or deformed joints.
Allergic hives and angioedema form when, in response to histamine, blood plasma leaks out of small blood vessels in the skin. Histamine is a chemical released from specialized cells along the skin’s blood vessels.
Evidence of systemic autoimmune disease, including hypothyroidism or hyperthyroidism (autoimmune thyroiditis); hepatitis, renal failure, and polyarthritis (cryoglobulinemia); malar rash, serositis, and polyarthritis (SLE); dry eyes and dry mouth (Sjögren syndrome); cutaneous ulcers or hypopigmented lesions after resolution of urticaria (urticarial vasculitis)
Urticaria is characterised by weals (hives) or angioedema (swellings, in 10%) or both (in 40%). There are several types of urticaria. The name urticaria is derived from the common European stinging nettle ‘Urtica dioica’.
Clinical Context:  Dapsone is the preferred sulfone. Other sulfones must be metabolized to dapsone for their effect. The mechanism of action is similar to that of sulfonamides in which competitive antagonists of PABA prevent the formation of folic acid, inhibiting bacterial growth.
Where a standard dose of a non-sedating H1 antihistamine is ineffective, doses of up to four times the standard dose may be used, or another antihistamine added. Evidence for up-titrating the dose varies[7]. An additional sedating antihistamine such as chlorphenamine may be useful if itch is interfering with sleep. Avoid hydroxyzine if the person has a prolonged QT interval risk factors for QT interval prolongation in line with recent guidance from the Medicines and Healthcare products Regulatory Agency (MHRA)[8].

“allergic reaction welts _treatment for urticarial vasculitis”

Text: “Skin Conditions: Hives (Urticaria and Angioedema)”,- WebMD Medical Reference provided in collaboration with the Cleveland Clinic,”Understanding Hives- Treatment”, – WebMD Medical Reference, “Allergic Reaction”- WebMD Medical Reference from eMedicineHealth
Apply calamine lotion. Calamine lotion is a mixture of zinc oxide and zinc carbonate. It can be applied to hives to relieve the itching as often as needed. When the itching subsides or you want to reapply, rinse off the calamine lotion with cool water.[13]
Discovering the exact cause of chronic urticaria is often extremely difficult. If the hives occur daily, they are most likely caused by something that you are exposed to daily. In that case, it is easier to see the cause/effect relationship. Sometimes it is several hours after exposure before the itching begins. In that case, some real detective work will be needed to find the culprit. These are the things to consider in order of importance: foods, drugs, infections, inhalants, and psychological factors.
There is a lot that we still do not understand about urticaria causes although we do know that there are certain triggers and certain reactions that could cause the symptoms associated with utricaria to flare up. The absence of any well defined or clear cause of urticaria does to a large extent limit our ability to deal with the problem. The point to note is that urticaria is not always caused through or because of an allergy and there is no definitive urticaria cure. Non–allergic causes are connected to auto- immunity, to hormone interplay to stress factors, and more. These are some of the more common urticaria causes or triggers:
; hives intensely itchy skin wheals; arise as hypersensitivity reaction, or on exposure to trigger substances (e.g. in foods, plants, drugs or other agents), or due to uraemia; characteristic of anaphylaxis
The hallmark red raised welts of hives sometimes have a pale center, can appear in clusters, and can change shape and location in a matter of hours. They can be from a few millimeters wide to as big as a dinner plate, and can itch, sting, or cause a burning sensation.
Most of the time, a doctor can diagnose hives just by looking at the skin. To find the cause, you may be asked questions about your child’s medical history, recent exposure to allergic triggers, and daily stressors.
Hives can be caused by an allergic reaction to foods, drugs, insect bites, infections or substances which can cause other allergic reactions. However not all cases are caused by allergy; frequently they are caused by viruses. It can sometimes be extremely difficult to find the cause. Triggers include medications, food, viruses, latex, heat, cold and direct exposure to sun. If the cause is known, the trigger should be avoided.
When you’re all stressed out, your body releases hormones and other chemicals, including histamine, the powerful chemical that leads to allergy symptoms. While stress doesn’t actually cause allergies, it can make an allergic reaction worse by increasing the histamine in your bloodstream.
In a small percentage of patients with chronic urticaria, perhaps about 2% [71], there is an underlying small vessel vasculitis. It is important to diagnose these patients because they may have an associated systemic illness which can lead to severe complications and because the treatment of urticarial vasculitis differs from that of ordinary chronic urticaria. Clinically, the lesions of urticarial vasculitis are longer-lasting (3–7 days) than those of ordinary chronic urticaria. They are often painful or ‘burning’ and they may leave residual bruising or hyperpigmentation of the skin. Approximately 40% of patients with urticarial vasculitis will have associated angioedema. Urticarial vasculitis may occur at any age, but the median age of incidence is 43 years. Women are affected twice as often as men. Two categories of urticarial vasculitis are recognized – hypocomplementaemic and normocomplementaemic [72]. Patients with hypocomplementaemic urticarial vasculitis syndrome (HUVS) are more likely to have an associated connective tissue disease and systemic symptoms than patients with normal complement levels [73] and may have IgG antibodies to the collagen-like domain of C1q [74]. There may be associated fever, arthralgia (50%), gastrointestinal involvement with abdominal pain, nausea, vomiting and diarrhoea (20%); pulmonary disease with dyspnoea or pulmonary effusions (20%); and glomerulonephritis with haematuria and proteinuria (5–10%). Progressive renal disease is rare, unless the urticarial vasculitis is associated with SLE. Other rare manifestations include eye involvement, lymphadenopathy, splenomegaly and pericardial effusions.
Yet another consideration is if you have an allergy to latex because a number of foods are known to produce a cross-reaction. Foods on this list include avocado, bananas, chestnuts, kiwi, and passion fruit.
Contrary to this opinion, William E. Berger, MD, MBA, professor of medicine at the University of California, tells WebMD that allergies create stress because you cannot focus on tasks and your coping skills decline.
Urticaria affects almost 20 percent of the population but the majority of the time, the cause is unknown (idiopathic). Even so, it is a good idea to try to find the trigger so you can possibly avoid it in the future.
Acute urticaria may develop in relation to a particular stressful event and it is recognized that financial, personal or professional stress may all worsen chronic urticaria. The condition itself may be very debilitating and it reduces quality of life [36].
Urticaria typically looks like a raised rash that may be a normal skin colour or pinkish or red in colour. The rash may occur anywhere on the body and often starts off as small round spots that quickly enlarge and spread.
Urticarial lesions itch, have a central white wheal that is elevated, and are surrounded by an erythematous halo. The lesions are typically rounded and circumscribed. Characteristically, hives should blanch with pressure; they generally resolve within 24 hours, leaving no residual change to the skin. The redness, which is augmented by local neural reflexes, is due to dilated blood vessels in superficial layers of the skin; the wheal is due to leakage of these vessels as fluid extravasates and compresses the vessels beneath it so that the central area appears clear.
Pressure-induced urticaria typically occurs 4-6 hours after pressure has been applied. Patients may complain of swelling secondary to pressure with normal-appearing skin (i.e., no erythema or superficial infiltrating hive), so that the term angioedema is more appropriate. Others are predominantly urticarial and may or may not be associated with significant swelling. Symptoms occur about tight clothing; the hands may swell with activity such as hammering; foot swelling is common after walking in patients with normal heart function; and buttock swelling may be prominent after sitting for a few hours.
Urticaria, commonly referred to as hives, is the most frequent dermatologic disorder seen in the emergency department (ED). It appears as raised, well-circumscribed areas of erythema and edema involving the dermis and epidermis that are very pruritic. Urticaria may be acute (lasting <6 wk) or chronic (lasting >6 wk). A large variety of urticaria variants exist, including acute immunoglobulin E (IgE)–mediated urticaria, chemical-induced urticaria (non-IgE-mediated), autoimmune urticaria, cholinergic urticaria, cold urticaria, mastocytosis, periodic fever syndromes including Muckle-Wells syndrome, and many others. [2, 10] While acute urticaria is generally related to an exogenous allergen or acute infection, chronic urticaria is more likely to be associated with autoimmunity. [8, 11, 12]
She’ll also ask about the you eat and if you have pets, to see if an allergy is to blame. She may check for other illnesses or conditions that could be causing the hives, like an overactive or underactive thyroid.
Delayed-pressure urticaria: Application of deep pressure to the skin produces swelling after 1-5 hours, like sitting on one spot for a prolonged period of time. The area will be deep and tender to touch.
Other drugs such as Colchicine, Warfarin, Nifedipine, Dapsone, Methotrexate and Sulfasalazine have been used with some success reported in chronic urticaria. Auto-immune thyroid disease with associated urticaria may respond to oral Thyroxine supplementation even if normal thyroid function. Immune suppressive therapy such as Cyclosporin is effective but can cause serious side effects such as kidney damage and uncontrolled hypertension.  Oral Sodium Cromoglycate may benefit Food related Exercise induced Urticaria. Stress (public speaking, examinations, exercise and arguments) may trigger Cholinergic Urticaria and Propranolol will reduce symptoms.
Morbidity depends on the severity and duration of the condition. One study found that urticaria patients can have as much psychologic, social, and occupational distress as patients who are awaiting triple coronary artery bypass surgery. [28]
If hives occur with swelling of the tongue or throat, difficulty breathing or low blood pressure, anaphylaxis should be suspected. Urgent administration of adrenaline and medical assessment is required. Information about anaphylaxis is available on the ASCIA website www.allergy.org.au/anaphylaxis
The Asthma and Allergy Foundation of America (AAFA), a not-for-profit organization founded in 1953, is the leading patient organization for people with asthma and allergies, and the oldest asthma and allergy patient group in the world.
The #1 best proven method of eliminating stress hives from your life forever is to remove ALL stress and tension from your life. Aside from that, the only other way is to take an OTC medication like OxyHives that has proven to get rid of hives within 1-2 hours. OxyHives has been around for over 10 years now and is effective without any of the harmful side effects other hives medications have. OxyHives recently received approval to sell their hives treatment over the counter and thus no longer requires a prescription. Please see our hives treatment page for more information.

“alcohol hives pictures of cholinergic urticaria”

Other forms of chronic urticaria include the physical urticarias, in which the rash is triggered by stimuli such as heat, cold, sunlight, pressure, and vibration. It is important to note that many forms of urticaria get worse with heat (such as from hot baths, exercise or wearing too much clothing) and pressure (such as around tight waistbands from clothing).
Jump up ^ Hirschmann, J. V.; Lawlor, F; English, JS; Louback, JB; Winkelmann, RK; Greaves, MW (1987). “Cholinergic Urticaria – A Clinical and Histologic Study”. Archives of Dermatology. 123 (4): 462–7. doi:10.1001/archderm.1987.01660280064024. PMID 3827277.
Contrary to this opinion, William E. Berger, MD, MBA, professor of medicine at the University of California, tells WebMD that allergies create stress because you cannot focus on tasks and your coping skills decline.
Steven A Conrad, MD, PhD is a member of the following medical societies: American College of Chest Physicians, American College of Critical Care Medicine, American College of Emergency Physicians, American College of Physicians, International Society for Heart and Lung Transplantation, Louisiana State Medical Society, Shock Society, Society for Academic Emergency Medicine, Society of Critical Care Medicine
Omalizumab, or Xolair, is an injectable drug that blocks immunoglobin E, a substance that plays a role in allergic responses. It can reduce symptoms of chronic idiopathic urticaria, a type of hives of unknown origin that can last for months or years.
It occurs in both men and women, but appears to be more common in men than women. The condition tends to first appear in people aged between 10 and 30 years and persists for a number of years before it becomes less severe or goes away altogether. The natural course of cholinergic urticaria is quite variable, with most patients experiencing slow resolution over several years.
If your GP thinks that it’s caused by an allergic reaction, you may be referred to an allergy clinic for an allergy test. However, if you’ve had urticaria most days for more than 6 weeks, it’s unlikely to be the result of an allergy.
Patients who have angioedema involving the oropharynx or any involvement of the airway should receive epinephrine 0.3 mL of 1:1000 solution sc and be admitted to the hospital. On discharge, patients should be supplied with and trained in the use of an auto-injectable epinephrine pen.
Solar urticaria: Treatment, management, and symptoms Solar urticaria is a type of rash that occurs after exposure to sunlight. Learn about the causes, symptoms, and how the condition is treated and prevented. Read now
Wong JT, Nagy CS, Krinzman SJ, Maclean JA, Bloch KJ. Rapid oral challenge-desensitization for patients with aspirin-related urticaria-angioedema. J Allergy Clin Immunol. 2000 May. 105(5):997-1001. [Medline].
When you have an allergic reaction to a substance, your body releases histamine and other chemicals into the blood. This causes itching, swelling, and other symptoms. Hives are a common reaction. People with other allergies, such as hay fever, often get hives.
Chronic hives can lead to severe discomfort, distress, and possibly depression. Stress, too, can aggravate hives, creating a vicious cycle. Patients who experience symptoms of depression should speak to a doctor.
It can be hard to figure out what causes chronic urticaria, though it’s sometimes linked to an immune system illness, like lupus. Other times, medications, food, insects, or an infection can trigger an outbreak. Often, though, doctors don’t know what causes chronic hives.
Both urticaria and angioedema are a result of histamine and other chemicals released from mast cells in the skin and mucous membranes. This may occur through an allergic process or one in which mast cells release chemicals without IgE being involved.
If your symptoms worsen or last longer than a couple of days, see your doctor. They can identify the cause and provide you with medication to help relieve your symptoms. Understanding what caused the hives is key to preventing future outbreaks.
Research shows that stress can play a major role in many physical and mental illnesses, including chronic idiopathic hives. “Stress can bring on and exacerbate chronic hives,” says Anand. “It’s not uncommon to see chronic idiopathic hives developing following a stressful period of time.” In several studies, people with chronic hives have been found to have higher levels of stress. Researchers have also found a link between post-traumatic stress disorder and hives. To lower stress, try relaxation techniques — for example, mindfulness meditation, which was found to lower the stress hormone cortisol in a study published in 2013 in the journal Health Psychology.
Hives are very common and are not considered contagious. Although annoying, hives usually resolve on their own over a period of weeks and are rarely medically Some hives may be caused by allergies to such things as foods, infections by different organisms, medications, food coloring, preservatives and insect stings or bites, and chemicals; but in the majority of cases, no specific cause is ever found. Although people may find it frustrating not to know what has caused their hives, maneuvers like changing diet, soap, detergent, and makeup are rarely helpful in preventing hives unless there is an excellent temporal relationship. Since hives most often are produced by an immune mechanism, the condition is not contagious. If an infectious disease were the cause of hives in a particular person then it is possible, but not likely, that an infected contact could develop hives.
Swellings, known as wheals, appear as a rash on the skin. They are usually pink or red, with an oval or round shape. They can range from a few millimeters to several inches across. They can be extremely itchy, and they have a red flare around them.
[Guideline] Magerl M, Borzova E, Gimrnez-Arnau A, Grattan CE, Lawlor F, Mathelier-Fusade P, et al. The definition and diagnostic testing of physical and cholinergic urticarias–EAACI/GA2LEN/EDF/UNEV consensus panel recommendations. Allergy. 2009 Dec. 64(12):1715-21. [Medline].
Jump up ^ Kolkhir, P.; Balakirski, G.; Merk, HF.; Olisova, O.; Maurer, M. (December 2015). “Chronic spontaneous urticaria and internal parasites – a systematic review”. Allergy. doi:10.1111/all.12818. PMID 26648083.
An alternative second-line treatment to H2 anti-histamines in patients who still have severe urticaria despite high-dose H1 anti-histamine treatment, is an LTRA such as montelukast or zafirlukast. LTRA treatment may be particularly effective if the patient is sensitive to aspirin or has a positive ASST [54]; however, urticaria does not always improve with LTRA and, very occasionally, patients notice worsening of the rash [55]– in which case they should stop the treatment. LTRA alone are not used for urticaria.
For some, the culprit is obvious—they’ll eat a peanut butter cookie, for example, and immediately break out in a rash. For others, it’s not so cut and dry; symptoms can take several hours to develop. Either way, make an appointment with your doctor if you suspect you have a food allergy. Dr. Jaliman says you’ll likely be put on an elimination diet where you reintroduce one potentially triggering food every week. “Let’s say you’re not eating any of the hives foods and then you add back shellfish and you get the hives again. Then you can pretty much figure it out,” Dr. Jaliman says. After you determine the culprit, nix it from your diet to prevent mild symptoms from becoming chronic. Dr. Jaliman says you’ll likely be prescribed an EpiPen—if you accidentally ingest a trigger food, you could get hives in your throat, which can be dangerous. 
An important variant to mention is urticarial vasculitis, which on initial presentation presents like urticaria but the lesions are non-migratory, last for more than 24 hours and resolve with postinflammatory hyperpigmentation.
A number of drugs, such as aspirin, NSAIDs, opiates, succinylcholine, and certain antibiotics (eg, polymyxin, ciprofloxacin, rifampin, vancomycin, some beta-lactams) can cause urticaria by a nonallergic mechanism rather than by IgE-mediated hypersensitivity.
Urticaria, commonly known as hives, is a distressing disorder affecting up to 20 percent of the population at some point in their lives. The swelling that sometimes accompanies urticaria, called angioedema, can lead to swelling of the face, hands and feet.
When a person has had hives for over six weeks, they are termed chronic urticaria. Many experts believe that acute and chronic urticaria are no different except for duration. Some studies indicate that allergy is less likely to be an underlying factor in chronic urticaria. Since in 80 per cent of the cases of chronic urticaria the underlying cause is never found, not many conclusions can be made.
If your hives last more than a month or if they recur over time, see an allergist, who will take a history and perform a thorough physical exam to determine the cause of your symptoms. A skin test and challenge test may also be needed to identify triggers.
Urticaria, also known as hives, is an outbreak of swollen, pale red bumps or plaques (wheals) on the skin that appear suddenly — either as a result of the body’s adverse reaction to certain allergens, or for unknown reasons.
Whenever possible, drug treatment should be avoided during pregnancy. Fortunately, chronic urticaria often improves in pregnancy; however, if symptoms are very severe and treatment is considered absolutely necessary, either chlorphenamine or loratidine may be prescribed. Data from several thousand women who had taken either chlorphenamine or loratidine in pregnancy, including data from several hundred who took anti-histamines during the first trimester [67,68], showed no increase in the incidence of fetal malformations. The lowest dose which controls symptoms should be used and the possibility of adverse effects should be discussed and documented. There is less clinical experience with cetirizine and therefore cetirizine is not recommended in pregnancy. Hydroxyzine is the only anti-histamine which is specifically contraindicated in pregnancy in the summary of product characteristics.
Hi I have found out I have this and been on many antihistamines to try and control it but I am now on fexafenidine and these don’t seem to work at all some days when I have a flare up I look like I…
Individual lesions of acute urticaria can appear at different locations and fade without scarring, often in a matter of hours. The development of urticaria can be an isolated event without systemic reaction or it can be a prelude to the development of an anaphylactic reaction. Although urticaria results from transient extravasation of plasma into the dermis, angioedema is the subcutaneous extension of urticaria that results in deep swelling within subcutaneous/submucosal tissues and is associated with pain.
Hives, also known as urticaria, is an outbreak of swollen, pale red bumps or plaques (wheals) that suddenly appear on the skin. Their appearance is usually the result of either the body’s reaction to certain allergens. Hives, generally speaking, cause and itchy feeling, but may also burn or sting. Common areas for hives to appear include the face, tongue, lips, throat and ears. It is important to note that hives don’t only come in one size, but rather they can carry from as small as a pencil eraser to as are as a hubcap. Hives, typically speaking, only last for a few hours up until a day, especially after treatment.
In some people hives are caused by physical triggers, including cold (such as cold air, water or ice), heat, sunlight (solar), vibration, rubbing or scratching of the skin (dermatographism) and delayed pressure (such as after carrying heavy bags.  In other people, exercise (sweating), stress, alcohol, spicy food or coffee may cause symptoms.
How do you get hives? Hives are not something you can “catch” from anyone. Rather, they are your body’s response to something it ingests or experiences. The cause of hives can be a certain food, drug, infection or stress. You might be surprised to learn that stress is one of the most common causes of acute hives, along with allergies and infectious causes. Hives can literally occur at any age and appear anywhere on the body. It is estimated that one in every five people will be affected by a hives outbreak at some point in his or her life. (2)